Microbiome modulation in inflammatory diseases: Progress to microbiome genetic engineering

F Mousavinasab, R Karimi, S Taheri… - Cancer Cell …, 2023 - Springer
Recent developments in sequencing technology and analytical approaches have allowed
researchers to show that the healthy gut microbiome is very varied and capable of …

Emerging frontiers in microbiome engineering

ME Inda, E Broset, TK Lu, C de la Fuente-Nunez - Trends in immunology, 2019 - cell.com
The gut microbiome has a significant impact on health and disease and can actively
contribute to obesity, diabetes, inflammatory bowel disease, cardiovascular disease, and …

Engineering the gut microbiome

X Bai, Z Huang, AM Duraj-Thatte, MP Ebert… - Nature Reviews …, 2023 - nature.com
The role of the gut microbiome in human health and disease is being increasingly
recognized. Gut microbes (including bacteria, fungi and viruses) can be genetically modified …

Emerging technologies for gut microbiome research

JW Arnold, J Roach, MA Azcarate-Peril - Trends in microbiology, 2016 - cell.com
Understanding the importance of the gut microbiome on modulation of host health has
become a subject of great interest for researchers across disciplines. As an intrinsically …

Microbiome regulation of autoimmune, gut and liver associated diseases

B Singh, N Qin, G Reid - Inflammation & Allergy-Drug Targets …, 2015 - ingentaconnect.com
Extensive analysis of the complexity and diversity of microbiota using metagenomics in the
gut and other body sites has provided evidence that dysbiosis occurs in many disease …

[HTML][HTML] Metabolic engineering in human gut microbiome: Recent developments and future perspectives

P Li, S Roos, H Luo, B Ji, J Nielsen - Metabolic Engineering, 2023 - Elsevier
Many studies have demonstrated that the gut microbiota is associated with human health
and disease. Manipulation of the gut microbiota, eg supplementation of probiotics, has been …

Gut microbiome interventions in human health and diseases

P Nie, Z Li, Y Wang, Y Zhang, M Zhao… - Medicinal research …, 2019 - Wiley Online Library
Ongoing studies have determined that the gut microbiota is a major factor influencing both
health and disease. Host genetic factors and environmental factors contribute to differences …

Modulating the human gut microbiome as an emerging therapeutic paradigm

DK Rajpal, JR Brown - Science progress, 2013 - journals.sagepub.com
The human body is actually a vast and changing ecosystem comprised of billions of
microbial organisms, known collectively as the microbiome. Within the last few years, the …

Mining the microbiome and microbiota-derived molecules in inflammatory bowel disease

M Bekkers, B Stojkovic, GE Kaiko - International Journal of Molecular …, 2021 - mdpi.com
The intestinal microbiota is a complex community that consists of an ecosystem with a
dynamic interplay between bacteria, fungi, archaea, and viruses. Recent advances in model …

[HTML][HTML] The human microbiota in health and disease

B Wang, M Yao, L Lv, Z Ling, L Li - Engineering, 2017 - Elsevier
Trillions of microbes have evolved with and continue to live on and within human beings. A
variety of environmental factors can affect intestinal microbial imbalance, which has a close …