Enzymatic glycosyl transfer: mechanisms and applications

T Desmet, W Soetaert - Biocatalysis and Biotransformation, 2011 - Taylor & Francis
Glycosylated compounds have numerous applications in the food, pharmaceutical and
personal care industries. Their synthesis is, however, far from trivial. Because chemical …

[HTML][HTML] Enzymatic glycosylation strategies in the production of bioactive compounds

A Andreu, M Ćorović, C Garcia-Sanz, AS Santos… - Catalysts, 2023 - mdpi.com
Enzymatic glycosylation is a versatile and sustainable biotechnological approach that plays
a pivotal role in the production of bioactive compounds. This process involves the enzymatic …

Enzymatic glycosylation of small molecules: challenging substrates require tailored catalysts

T Desmet, W Soetaert, P Bojarová… - … A European Journal, 2012 - Wiley Online Library
Glycosylation can significantly improve the physicochemical and biological properties of
small molecules like vitamins, antibiotics, flavors, and fragrances. The chemical synthesis of …

Plant glycosyltransferases: their potential as novel biocatalysts

EK Lim - Chemistry–A European Journal, 2005 - Wiley Online Library
The potential application of glycosyltransferases in glycoconjugate synthesis has attracted
considerable interest from the biotechnology community in recent years. This concept article …

Glycosyltransferase-catalyzed synthesis of non-natural oligosaccharides

R Öhrlein - Biocatalysis-From Discovery to Application, 1999 - Springer
Enzymes are indispensable tools in modern organic synthesis. Recent progress in cloning
techniques, microbiology and protein purification supply an ever growing number and …

Glycosyltransferases as biocatalysts

MM Palcic - Current Opinion in Chemical Biology, 2011 - Elsevier
Glycosyltransferases are useful synthetic tools for the preparation of natural
oligosaccharides, glycoconjugates and their analogues. High expression levels of …

Research progress and application of enzymatic synthesis of glycosyl compounds

Y Shen, Y Xia, X Chen - Applied Microbiology and Biotechnology, 2023 - Springer
Glucoside compounds are widely found in nature and have garnered significant attention in
the medical, cosmetics, and food industries due to their diverse pharmaceutical properties …

Teaching old enzymes new tricks: engineering and evolution of glycosidases and glycosyl transferases for improved glycoside synthesis

FA Shaikh, SG Withers - Biochemistry and Cell Biology, 2008 - cdnsciencepub.com
The therapeutic potential of glycosides has made them an attractive target for drug
development. The biological extraction and chemical synthesis of these molecules is often …

Recent biotechnological progress in enzymatic synthesis of glycosides

NH Thuan, JK Sohng - Journal of Industrial Microbiology and …, 2013 - academic.oup.com
Glycosylation is one of the most important post-modification processes of small molecules
and enables the parent molecule to have increased solubility, stability, and bioactivity …

Features and applications of bacterial glycosyltransferases: current state and prospects

A Luzhetskyy, A Bechthold - Applied microbiology and biotechnology, 2008 - Springer
The bioactivity of many natural products including valuable antibiotics and anticancer
therapeutics depends on their sugar moieties. Changes in the structures of these sugars can …