Leptin influences satiety, adiposity, and metabolism and is associated with mechanisms
regulating puberty onset, fertility, and pregnancy in various species. Maternal …

Leptin is a polypeptide hormone that aids in the regulation of body weight and energy
homeostasis and is linked to a variety of reproductive processes in both animals and …

Leptin is a hormone that is secreted by adipose cells in proportion to adipose mass, and
therefore a low leptin level signifies depletion of energy stores. It has been proposed that …

Leptin, which was identified originally as an adipocyte-derived protein, was regarded for
years as an exclusive regulator of satiety and energy homeostasis. A role for leptin in …

Leptin was initially identified as an adipocyte-derived hormone that decreases food intake
and body weight via its receptor in the hypothalamus. Subsequent animal studies revealed …

Leptin, the product of the ob gene, is a small peptide molecule synthesized by white
adipocytes with an important role in the regulation of body fat and food intake. Leptin and …

Leptin is expressed in the placenta and in certain fetal tissues; however, little is known with
regard to the function of this hormone in these tissues. To date, most evidence suggests that …

Leptin levels are significantly elevated in pregnant mice, rats and humans suggesting a
critical role for leptin during gestation. To address whether leptin plays a putative role in the …

Placental tissues from humans, rodents and farm animals contain leptin and its receptor.
Leptin produced by the human placenta has the same size, charge and immunoreactivity as …

Leptin has recently been implicated as having a role in sexual maturation and reproduction.
This review describes recent findings regarding the putative reproductive functions of leptin …