Atomic force microscopy: high resolution dynamic imaging of cellular and molecular structure in health and disease

DJ Taatjes, AS Quinn, JH Rand… - Journal of cellular …, 2013 - Wiley Online Library
The atomic force microscope (AFM), invented in 1986, and a member of the scanning probe
family of microscopes, offers the unprecedented ability to image biological samples unfixed …

Atomic force microscopy probing in the measurement of cell mechanics

D Kirmizis, S Logothetidis - International journal of nanomedicine, 2010 - Taylor & Francis
Atomic force microscope (AFM) has been used incrementally over the last decade in cell
biology. Beyond its usefulness in high resolution imaging, AFM also has unique capabilities …

Recent advances in the application of atomic force microscopy to structural biology

AC Dumitru, M Koehler - Journal of Structural Biology, 2023 - Elsevier
The application of atomic force microscopy (AFM) for functional imaging and manipulating
biomolecules at all levels of organization has enabled great progress in the structural …

Atomic force microscopy in the study of macromolecular interactions in hemostasis and thrombosis: utility for investigation of the antiphospholipid syndrome

WJ Montigny, AS Quinn, XX Wu… - … in biology and …, 2006 - Wiley Online Library
This chapter demonstrates the unmatched efficacy of atomic force microscopy (AFM) for the
investigation of interactions occurring between biological cell-surface macromolecules on …

[HTML][HTML] Nano-scientific application of atomic force microscopy in pathology: from molecules to tissues

TM Kiio, S Park - International Journal of Medical Sciences, 2020 - ncbi.nlm.nih.gov
The advantages of atomic force microscopy (AFM) in biological research are its high
imaging resolution, sensitivity, and ability to operate in physiological conditions. Over the …

Atomic force microscopy probing of cell elasticity

TG Kuznetsova, MN Starodubtseva, NI Yegorenkov… - Micron, 2007 - Elsevier
Atomic force microscopy (AFM) has recently provided the great progress in the study of
micro-and nanostructures including living cells and cell organelles. Modern AFM techniques …

Atomic force microscopy in disease‐related studies: Exploring tissue and cell mechanics

S Liu, Y Han, L Kong, G Wang… - Microscopy Research and …, 2024 - Wiley Online Library
Despite significant progress in human medicine, certain diseases remain challenging to
promptly diagnose and treat. Hence, the imperative lies in the development of more …

Biological applications of atomic force microscopy

R Lal, SA John - American Journal of Physiology-Cell …, 1994 - journals.physiology.org
The newly developed atomic force microscope (AFM) provides a unique window to the
microworld of cells, subcellular structures, and biomolecules. The AFM can image the three …

Atomic force microscopy in structural biology: from the subcellular to the submolecular

DM Czajkowsky, H Iwamoto, Z Shao - Microscopy, 2000 - ieeexplore.ieee.org
Atomic force microscopy (AFM) is capable of generating images within ranges of resolution
that are of particular interest in biology. Although atomic resolution may not be possible with …

Providing unique insight into cell biology via atomic force microscopy

V Shahin, NP Barrera - International review of cytology, 2008 - Elsevier
The invention of atomic force microscopy (AFM) some two decades ago opened up new
realms for our perception of cell biology. AFM produces three-dimensional images of …