Protective effect of baicalin on the regulation of Treg/Th17 balance, gut microbiota and short-chain fatty acids in rats with ulcerative colitis

L Zhu, LZ Xu, S Zhao, ZF Shen, H Shen… - Applied Microbiology and …, 2020 - Springer
Baicalin is reported as an effective drug for ulcerative colitis (UC). However, its effect on gut
microbiota and short-chain fatty acids (SCFAs) remains unknown. In this study, we …

[HTML][HTML] Baitouweng Tang ameliorates DSS-induced ulcerative colitis through the regulation of the gut microbiota and bile acids via pathways involving FXR and …

YL Hua, YQ Jia, X Zhang, ZW Yuan, P Ji, JJ Hu… - Biomedicine & …, 2021 - Elsevier
Abstract In China, Baitouweng Tang (BTWT) is a commonly prescribed remedy for the
treatment of ulcerative colitis (UC). Herein, the present study aims to assess the anti-colitis …

[HTML][HTML] Berberine regulates Treg/Th17 balance to treat ulcerative colitis through modulating the gut microbiota in the colon

H Cui, Y Cai, L Wang, B Jia, J Li, S Zhao… - Frontiers in …, 2018 - frontiersin.org
Berberine (BBR), an alkaloid isolated from Rhizoma Coptidis, Cortex Phellode, and
Berberis, has been widely used in the treatment of ulcerative colitis (UC). However, the …

[HTML][HTML] 5-Aminosalicylic acid ameliorates dextran sulfate sodium-induced colitis in mice by modulating gut microbiota and bile acid metabolism

L Huang, J Zheng, G Sun, H Yang, X Sun… - Cellular and Molecular …, 2022 - Springer
Colitis develops via the convergence of environmental, microbial, immunological, and
genetic factors. The medicine 5-aminosalicylic acid (5-ASA) is widely used in clinical …

Fucoidan ameliorated dextran sulfate sodium-induced ulcerative colitis by modulating gut microbiota and bile acid metabolism

X Liu, Y Zhang, W Li, B Zhang, J Yin… - Journal of agricultural …, 2022 - ACS Publications
Gut dysbiosis and bile acid (BA) metabolism disturbance are involved in the pathogenesis of
ulcerative colitis. This study aimed to investigate the effect of fucoidan on BA metabolism …

Berberine ameliorates colonic damage accompanied with the modulation of dysfunctional bacteria and functions in ulcerative colitis rats

Z Liao, Y Xie, B Zhou, B Zou, D Xiao, W Liu… - Applied microbiology …, 2020 - Springer
Intestinal flora imbalance is one of the potential pathogenesis of inflammatory bowel
diseases, and the study aims to discover the effect of berberine on the composition and …

[HTML][HTML] Berberine ameliorates DSS-induced intestinal mucosal barrier dysfunction through microbiota-dependence and Wnt/β-catenin pathway

Y Dong, H Fan, Z Zhang, F Jiang, M Li… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Ulcerative colitis (UC) is an idiopathic, chronic inflammatory disorder of the colon, and it has
become one of the world-recognized medical problems as it is recurrent and refractory …

[HTML][HTML] Prevention of Ulcerative Colitis in Mice by Sweet Tea (Lithocarpus litseifolius) via the Regulation of Gut Microbiota and Butyric-Acid-Mediated Anti …

XQ He, D Liu, HY Liu, DT Wu, HB Li, XS Zhang… - Nutrients, 2022 - mdpi.com
Sweet tea (Lithocarpus litseifolius [Hance] Chun) is a new resource for food raw materials,
with plenty of health functions. This study aimed to investigate the preventive effect and …

Baicalin may alleviate inflammatory infiltration in dextran sodium sulfate-induced chronic ulcerative colitis via inhibiting IL-33 expression

CL Zhang, S Zhang, WX He, JL Lu, YJ Xu, JY Yang… - Life sciences, 2017 - Elsevier
Aims To investigate the therapeutic effect of baicalin treatment in chronic ulcerative colitis
(UC), and explore the potential anti-inflammation mechanism (s) via IL-33 pathway. Main …

Faecalibacterium prausnitzii Produces Butyrate to Maintain Th17/Treg Balance and to Ameliorate Colorectal Colitis by Inhibiting Histone Deacetylase 1

L Zhou, M Zhang, Y Wang, RG Dorfman… - Inflammatory bowel …, 2018 - academic.oup.com
Background Inflammatory bowel disease (IBD)–associated dysbiosis is characterized by a
loss of Faecalibacterium prausnitzii, whose supernatant exerts an anti-inflammatory effect …