A hallmark of chronic kidney disease is the retention of solutes that normally are eliminated
by the kidneys. The current classification defines uremic toxins based on molecular weight …

Progress in the identification and characterization of uremic retention solutes has refined our
understanding of the pathophysiology of the uremic syndrome. Furthermore, the evolution of …

Patients with end-stage kidney disease (ESKD) on maintenance hemodialysis are subject to
a high burden of inflammation and cardiovascular disease, driven at least in part by …

A convenient way to classify uremic solutes is to subdivide them according to the
physicochemical characteristics influencing their dialytic removal into small water‐soluble …

Chronic kidney disease is characterized by the accumulation of organic compounds in the
bloodstream that may exert a variety of toxic effects in the body. These compounds …

Advances in our understanding of uremic retention solutes, and improvements in
hemodialysis membranes and other techniques designed to remove uremic retention …

Accumulation of uremic toxins induces various uremia-related complications in patients with
chronic kidney disease, particularly those undergoing dialysis treatment. Direct interactions …

Chronic kidney disease (CKD) is a condition that affects approximately 10% of the adult
population in developed countries. In patients with CKD adequate renal clearance is …

This publication reviews the currently available methods to identify uremic retention solutes,
to determine their biological relevance and to quantify their removal. The analytical methods …

Chronic kidney disease (CKD) is characterized by the progressive retention of a myriad of
compounds, several of which play a role in cardiovascular damage, a major cause of …