Targeted metabolomics for the quantitative measurement of 9 gut microbiota–host co-metabolites in rat serum, urine and feces by liquid chromatography–tandem …

Y Zeng, Y Lin, L Li, Y Li, X Zhang, M Wang… - … of Chromatography B, 2019 - Elsevier
Gut microbiota–host co-metabolites play an essential role in maintaining homeostasis, and
their concentration changes are closely related to a variety of diseases. Developing a …

A strategy for the targeted metabolomics analysis of 11 gut microbiota-host co-metabolites in rat serum, urine and feces by ultra high performance liquid …

W Hou, D Zhong, P Zhang, Y Li, M Lin, G Liu… - … of Chromatography A, 2016 - Elsevier
Microbiota-host co-metabolites are well-known to play important physiological roles, and
their dysregulation has been found to be closely related to various diseases, including but …

Uncovering the Carboxylated Metabolome in Gut Microbiota–Host Co-metabolism: A Chemical Derivatization-Molecular Networking Approach

YZ Wang, YY Chen, XZ Wu, PR Bai, N An… - Analytical …, 2023 - ACS Publications
Gut microbiota–host co-metabolites serve as essential mediators of communication between
the host and gut microbiota. They provide nutrient sources for host cells and regulate gut …

Strategy for Comprehensive Detection and Annotation of Gut Microbiota-Related Metabolites Based on Liquid Chromatography–High-Resolution Mass Spectrometry

S Zheng, W Qin, T Chen, R Ouyang, X Wang… - Analytical …, 2024 - ACS Publications
Gut microbiota, widely populating the mammalian gastrointestinal tract, plays an important
role in regulating diverse pathophysiological processes by producing bioactive molecules …

Quantifying the human diet in the crosstalk between nutrition and health by multi-targeted metabolomics of food and microbiota-derived metabolites

R González-Domínguez, O Jáuregui, P Mena… - International Journal of …, 2020 - nature.com
Background Metabolomics is a powerful tool for investigating the association between
nutrition and health status. Although urine is commonly employed for studying the …

Development of a simultaneous quantification method for the gut microbiota-derived core nutrient metabolome in mice and its application in studying host-microbiota …

H Xu, J Wang, Y Liu, Y Wang, X Zhong, C Li… - Analytica Chimica …, 2023 - Elsevier
The gut microbiota interacts with the host via production of various metabolites of dietary
nutrients. Herein, we proposed the concept of the gut microbiota-derived core nutrient …

[HTML][HTML] Gut microbiota profiling: metabolomics based approach to unravel compounds affecting human health

P Vernocchi, F Del Chierico, L Putignani - Frontiers in microbiology, 2016 - frontiersin.org
The gut microbiota is composed of a huge number of different bacteria, that produce a large
amount of compounds playing a key role in microbe selection and in the construction of a …

Gut microbiota-related metabolome analysis based on chromatography-mass spectrometry

L Zhou, D Yu, S Zheng, R Ouyang, Y Wang… - TrAC Trends in Analytical …, 2021 - Elsevier
Gut microbiota can either contribute to the host development and health, or lead to the
pathogenesis of various diseases in the case of imbalance. Microbial metabolites can act as …

Assessment of Biphasic Extraction Methods of Mouse Fecal Metabolites for Liquid Chromatography–Mass Spectrometry-Based Metabolomic Studies

S Yu, J Fan, L Zhang, X Qin, Z Li - Journal of Proteome Research, 2021 - ACS Publications
With the increasing knowledge about the important roles of gut microbiota on the biological
system, a systematic strategy to profile the fecal metabolome is urgently needed. Thus, an …

[HTML][HTML] A New Biomarker Profiling Strategy for Gut Microbiome Research: Valid Association of Metabolites to Metabolism of Microbiota Detected by Non-Targeted …

S Zheng, L Zhou, M Hoene, A Peter, AL Birkenfeld… - Metabolites, 2023 - mdpi.com
The gut microbiome is of tremendous relevance to human health and disease, so it is a hot
topic of omics-driven biomedical research. However, a valid identification of gut microbiota …