[HTML][HTML] Liquiritigenin reduces osteoclast activity in zebrafish model of glucocorticoid-induced osteoporosis

M Carnovali, G Banfi, M Mariotti - Journal of Pharmacological sciences, 2020 - Elsevier
Drug and therapies currently used to treat human bone diseases have a lot of severe side
effects. Liquiritigenin is a flavonoid extracted from Glycyrrhiza glabra roots which has been …

Dual effects of liquiritigenin on the proliferation of bone cells: Promotion of osteoblast differentiation and inhibition of osteoclast differentiation

K Uchino, K Okamoto, E Sakai… - Phytotherapy …, 2015 - Wiley Online Library
Bone is constantly controlled by a balance between osteoblastic bone formation and
osteoclastic bone resorption. Liquiritigenin is a plant‐derived flavonoid and has various …

Liquiritigenin isolated from Glycyrrhiza uralensis stimulates osteoblast function in osteoblastic MC3T3-E1 cells

EM Choi - International immunopharmacology, 2012 - Elsevier
Liquiritigenin is one of the flavonoids present in Glycyrrhizae radix. In the present study, the
effects of liquiritigenin on the function of osteoblastic MC3T3-E1 cells were studied …

Liquiritigenin reduces blood glucose level and bone adverse effects in hyperglycemic adult zebrafish

M Carnovali, L Luzi, I Terruzzi, G Banfi, M Mariotti - Nutrients, 2019 - mdpi.com
Diabetes mellitus is a metabolic disease characterized by chronic hyperglycemia that
induces other pathologies including diabetic retinopathy and bone disease. Adult Danio …

Ligustilide, a major bioactive component of Angelica sinensis, promotes bone formation via the GPR30/EGFR pathway

F Yang, ZW Lin, TY Huang, TT Chen, J Cui, MY Li… - Scientific Reports, 2019 - nature.com
Abstract Angelica sinensis (Oliv.) Diels is a widely-used traditional Chinese herbal medicine
in treating osteoporosis. Ligustilide (LIG) is the main component of A. sinensis and is …

Epimedin C alleviates glucocorticoid-induced suppression of osteogenic differentiation by modulating PI3K/AKT/RUNX2 signaling pathway

Y Xu, S Chen, L Huang, W Han, Y Shao… - Frontiers in …, 2022 - frontiersin.org
Secondary osteoporosis is triggered mostly by glucocorticoid (GC) therapy. Dexamethasone
(DEX) was reported to inhibit osteogenic differentiation in zebrafish larvae and MC3T3-E1 …

Gu Sui Bu (Drynaria fortunei J. Sm.) antagonizes glucocorticoid-induced mineralization reduction in zebrafish larvae by modulating the activity of osteoblasts and …

CH Peng, WY Lin, CY Li, KK Dharini, CY Chang… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Gu Sui Bu (GSB), the dried rhizome of Drynaria
fortunei J. Sm., is widely used in traditional Chinese medicine for treating fractures and …

10-gingerol suppresses osteoclastogenesis in RAW264. 7 cells and zebrafish osteoporotic scales

L Zang, K Kagotani, H Nakayama, J Bhagat… - Frontiers in Cell and …, 2021 - frontiersin.org
Osteoporosis is the most common aging-associated bone disease and is caused by
hyperactivation of osteoclastic activity. We previously reported that the hexane extract of …

[HTML][HTML] Tanshinol stimulates bone formation and attenuates dexamethasone-induced inhibition of osteogenesis in larval zebrafish

S Luo, Y Yang, J Chen, Z Zhong, H Huang… - Journal of Orthopaedic …, 2016 - Elsevier
Summary Background/Objective Tanshinol is the main active component of Salvia
miltiorrhiza Bunge, a significant Traditional Chinese Medicine used to treat cardiovascular …

Efficacy of the herbal pair, Radix Achyranthis Bidentatae and Eucommiae Cortex, in preventing glucocorticoid-induced osteoporosis in the zebrafish model

J Lee, Y Wei, Z Zhou, Y Hou, C Wang, L Wang… - Journal of Integrative …, 2022 - Elsevier
Abstract Objective In traditional Chinese medicine, the herbal pair, Radix Achyranthis
Bidentatae (RAB) and Eucommiae Cortex (EC), is widely used to treat osteoporosis. Herein …