Human malaria, caused by five Plasmodium species (P. falciparum, P. vivax, P. malariae, P.
ovale, and P. knowlesi), remains a significant global health burden. While most interventions …

Malaria is a complex parasitic disease that is currently causing great concerns globally
owing to the resistance to antimalarial drugs and lack of an effective vaccine. The present …

Passive transfer studies in humans clearly demonstrated the protective role of IgG
antibodies against malaria. Identifying the precise parasite antigens that mediate immunity is …

Efforts to develop vaccines against malaria represent a major research target. The
observations that 1) sterile protection can be obtained when the host is exposed to live …

The Plasmodium parasite, the causative agent of malaria, is an excellent model for
immunomic-based approaches to vaccine development. The Plasmodium parasite has a …

With the completion of the functional genome, merozoite proteome and stage-specific
transcriptomes of the intraerythrocytic developmental cycle of Plasmoidum falciparum, the …

Completed genome sequences and stage-specific transcriptomes of the intraerythrocytic
developmental cycle of Plasmodium vivax offers the opportunity to profile immune …

The development of an effective malaria vaccine remains a global public health priority.
Less than 0.5% of the Plasmodium falciparum genome has been assessed as potential …

Advancement in the field of proteomics and bioinformatics offers tremendous opportunities
for the development of novel epitope-based effective vaccine against human malaria. In this …

Completion of sequencing of the Plasmodium vivax genome and transcriptome offers the
chance to identify antigens among> 5000 candidate proteins. To identify those P. vivax …