Regenerative medicine for the treatment of ischemic heart disease; status and future perspectives

B Arjmand, M Abedi, M Arabi… - Frontiers in Cell and …, 2021 - frontiersin.org
Cardiovascular disease is now the leading cause of adult death in the world. According to
new estimates from the World Health Organization, myocardial infarction (MI) is responsible …

Mesenchymal stem cell insights: prospects in cardiovascular therapy

SH Chou, SZ Lin, WW Kuo, P Pai, JY Lin… - Cell …, 2014 - journals.sagepub.com
Ischemic heart damage usually triggers cardiomyopathological remodeling and fibrosis, thus
promoting the development of heart functional failure. Mesenchymal stem cells (MSCs) are a …

Cardiac repair and the putative role of stem cells

LM Buja - Journal of Molecular and Cellular Cardiology, 2019 - Elsevier
Stem cell biology has informed and energized cardiac regenerative medicine. The field is
linked to a construct that challenges long-standing concepts and advances the basic tenets …

Myocardial infarction and stem cells

KA Krishna, KS Krishna, R Berrocal… - Journal of Pharmacy …, 2011 - journals.lww.com
Permanent loss of cardiomyocytes and scar tissue formation after myocardial infarction (MI)
results in an irreversible damage to the cardiac function. Cardiac repair (replacement …

Regenerative cardiovascular therapies: stem cells and beyond

B Wernly, M Mirna, R Rezar, C Prodinger… - International journal of …, 2019 - mdpi.com
Although reperfusion therapy has improved outcomes, acute myocardial infarction (AMI) is
still associated with both significant mortality and morbidity. Once irreversible myocardial cell …

[HTML][HTML] Advances in stem cell therapy for cardiovascular disease

R Sun, X Li, M Liu, Y Zeng… - … journal of molecular …, 2016 - spandidos-publications.com
Cardiovascular disease constitutes the primary cause of mortality and morbidity worldwide,
and represents a group of disorders associated with the loss of cardiac function. Despite …

Mesenchymal stem cells in cardiac regeneration: a detailed progress report of the last 6 years (2010–2015)

A Singh, A Singh, D Sen - Stem cell research & therapy, 2016 - Springer
Mesenchymal stem cells have been used for cardiovascular regenerative therapy for
decades. These cells have been established as one of the potential therapeutic agents …

The future of cardiovascular regenerative medicine

RT Lee, K Walsh - Circulation, 2016 - Am Heart Assoc
Lee and Walsh Future of Cardiovascular Regenerative Medicine 2619 cells by using
reprogramming factors. 16 This monumental achievement meant that potentially any cell …

Myocardial infarction: stem cell transplantation for cardiac regeneration

E Carvalho, P Verma, K Hourigan… - Regenerative …, 2015 - Taylor & Francis
It is estimated that by 2030, almost 23.6 million people will perish from cardiovascular
disease, according to the WHO. The review discusses advances in stem cell therapy for …

[HTML][HTML] Optimizing stem cells for cardiac repair: current status and new frontiers in regenerative cardiology

S Der Sarkissian, T Lévesque… - World journal of stem …, 2017 - ncbi.nlm.nih.gov
Cell therapy has the potential to improve healing of ischemic heart, repopulate injured
myocardium and restore cardiac function. The tremendous hope and potential of stem cell …