Aims Mild traumatic brain injury (mTBI) is an important risk factor for cognitive impairment.
Despite intense efforts to develop efficient treatments, the current therapies are not often …

Silymarin and silibinin are bioactive components isolated from Silybum marianum. They
have been reported to exhibit anti-oxidative and anti-inflammatory effects. Many studies …

Cerebral stroke is the third largest cause of death and the severe leading cause of disability,
thus have astronomical financial and social burden worldwide. Accumulated evidence …

Silibinin, a flavonoid derived from the herb milk thistle (Silybum marianum), has been used
as a hepato-protectant in the clinical treatment of liver disease. In the present study, the …

Background Silymarin is a polyphenolic flavanoid of Silybum marianum, elicited
neuroprotection and antidepressant like activity in stressed model. It was found to increase 5 …

Cognitive deficits are a core feature of patients with methamphetamine (METH) abuse. It has
been reported that repeated METH treatment impairs long-term recognition memory in the …

The aim of our study was to investigate the protective effects and underlying mechanisms of
myricetin, a bioactive food compound, on brain injury and neurological deficits after ischemic …

Aims There is increasing evidence showing that mild traumatic brain injury (mTBI) is
associated with increased depression-related disorders in humans. Recent studies suggest …

Simvastatin, a cholesterol-lowering agent, has demonstrated neuroprotective effects against
brain injury, but the underlying mechanisms remain unclear. This study was undertaken to …

Silymarin, a C25 containing flavonoid from the plant Silybum marianum, has been the gold
standard drug to treat liver disorders associated with alcohol consumption, acute and …