[PDF][PDF] Single neuronal and glial gene expression in the nucleus tractus solitarius in an alcohol withdrawal time series reveals novel cellular phenotypes and networks

SJ O'Sullivan, D McIntosh-Clarke, J Park, R Vadigepalli… - 2021 - pdfs.semanticscholar.org
Alcohol withdrawal syndrome (AWS) is characterized by neuronal hyperexcitability,
autonomic dysregulation, and severe negative emotion. The nucleus tractus solitarius (NTS) …

Single cell scale neuronal and glial gene expression and putative cell phenotypes and networks in the nucleus tractus solitarius in an alcohol withdrawal time series

SJ O'Sullivan, D McIntosh-Clarke, J Park… - Frontiers in Systems …, 2021 - frontiersin.org
Alcohol withdrawal syndrome (AWS) is characterized by neuronal hyperexcitability,
autonomic dysregulation, and severe negative emotion. The nucleus tractus solitarius (NTS) …

Transcriptome changes in the nucleus of the solitary tract induced by repeated stress, alcohol dependence, or stress-induced drinking in dependent mice

EK Grantham, GR Tiwari, O Ponomareva, RA Harris… - …, 2024 - Elsevier
Stress increases alcohol consumption in dependent animals and contributes to the
development of alcohol use disorder. The nucleus of the solitary tract (NTS) is a critical …

Transcriptome analysis of alcohol dependence and stress interactions in the nucleus of the solitary tract

EK Grantham, GR Tiwari, O Ponomereva, AS Warden… - bioRxiv, 2022 - biorxiv.org
Stress exposure contributes to the development of drug and alcohol use disorders. In animal
models, stress exacerbates escalations in alcohol consumption in alcohol-dependent …

The Effect of Alcohol and Opioid Withdrawal on Single-Cell Glia and Neuronal Gene Expression in the Visceral Emotional Neuraxis

S O'Sullivan - 2021 - search.proquest.com
Alcohol and opioid abuse pose major social, economic, and health-related consequences to
society. These depressants have distinct yet overlapping effects on mammalian systems …

Chronic alcohol exposure alters transcription broadly in a key integrative brain nucleus for homeostasis: the nucleus tractus solitarius

MY Covarrubias, RL Khan… - Physiological …, 2006 - journals.physiology.org
Chronic exposure to alcohol modifies physiological processes in the brain, and the severe
symptoms resulting from sudden removal of alcohol from the diet indicate that these …

Molecular pathways in alcohol consumption and dependence: emphasis on gut-brain and neuroimmune signaling

EK Grantham - 2021 - repositories.lib.utexas.edu
Alcohol use disorder (AUD) is a chronic, relapsing brain disease with few effective treatment
options. Chronic alcohol abuse leads to cellular and molecular changes throughout the …

[HTML][HTML] Single-cell profiling of glial cells from the mouse amygdala under opioid dependent and withdrawal states

Y Yan, B Truitt, J Tao, SM Boyles, D Antoine, W Hulme… - Iscience, 2023 - cell.com
The cycle of substance use disorder (SUD) leading to dependence is a complex process
involving multiple neurocircuitries and brain regions. The amygdala is the core brain region …

The role of alcohol in modifying behavior

J Peters, L Trabace, G Di Giovanni - Frontiers in Behavioral …, 2023 - frontiersin.org
This special topic presents experimental work on the effects of alcohol (ethanol) on the
brain, and how these effects impact behavior across multiple domains. The World Health …

Glial gene networks associated with alcohol dependence

EK Erickson, YA Blednov, RA Harris, RD Mayfield - Scientific reports, 2019 - nature.com
Chronic alcohol abuse alters the molecular structure and function of brain cells. Recent work
suggests adaptations made by glial cells, such as astrocytes and microglia, regulate …