Sex and acetazolamide effects on chemoreflex and periodic breathing during sleep at altitude

S Caravita, A Faini, C Lombardi, M Valentini… - Chest, 2015 - Elsevier
OBJECTIVE Nocturnal periodic breathing occurs more frequently in men than in women with
various clinical and pathophysiologic conditions. The mechanisms accounting for this sex …

Breathing and sleep at high altitude

PN Ainslie, SJE Lucas, KR Burgess - Respiratory physiology & …, 2013 - Elsevier
We provide an updated review on the current understanding of breathing and sleep at high
altitude in humans. We conclude that:(1) progressive changes in pH initiated by the …

High‐altitude hypoxia and periodic breathing during sleep: gender‐related differences

C Lombardi, P Meriggi, P Agostoni… - Journal of sleep …, 2013 - Wiley Online Library
High‐altitude exposure is characterized by the appearance of periodic breathing during
sleep. Only limited evidence is available, however, on the presence of gender‐related …

Sex-related differences in loop gain during high-altitude sleep-disordered breathing

JD Bird, SA Sands, RM Alex, CLH Shing… - Annals of the …, 2023 - atsjournals.org
Rationale: Central sleep apnea (CSA) is pervasive during sleep at high altitude,
disproportionately impacting men and associated with increased peripheral …

Altitude illness is related to low hypoxic chemoresponse and low oxygenation during sleep

H Nespoulet, B Wuyam, R Tamisier… - European …, 2012 - Eur Respiratory Soc
Altitude illness remains a major cause of mortality. Reduced chemosensitivity, irregular
breathing leading to central apnoeas/hypopnoeas, and exaggerated pulmonary …

Effect of altitude and acetazolamide on sleep and nocturnal breathing in healthy lowlanders 40 y of age or older. Data from a randomized trial

LC Graf, M Furian, K Bitos, M Mademilov, A Abdraeva… - Sleep, 2023 - academic.oup.com
Abstract Study Objectives To assess altitude-induced sleep and nocturnal breathing
disturbances in healthy lowlanders 40 y of age or older and the effects of preventive …

Chemoreflex mediated arrhythmia during apnea at 5,050 m in low-but not high-altitude natives

SA Busch, H Davies, S Van Diepen… - Journal of Applied …, 2018 - journals.physiology.org
Peripheral chemoreflex mediated increases in both parasympathetic and sympathetic drive
under chronic hypoxia may evoke bradyarrhythmias during apneic periods. We determined …

[HTML][HTML] Periodic breathing in healthy young adults in normobaric hypoxia equivalent to 3500 m, 4500 m, and 5500 m altitude

S Pramsohler, R Schilz, A Patzak, L Rausch… - Sleep and …, 2019 - Springer
Purpose The occurrence of periodic breathing (PB) at high altitude during sleep and the
quality of sleep are individually different and influenced by multiple factors including sex …

Dynamics of periodic breathing and arousal during sleep at extreme altitude

MCK Khoo, JD Anholm, SW Ko, R Downey III… - Respiration …, 1996 - Elsevier
To determine whether nocturnal periodic breathing (PB) at altitude is due primarily to
unstable control of ventilation or the inability to maintain stable sleep states, we performed …

Time of day affects the frequency and duration of breathing events and the critical closing pressure during NREM sleep in participants with sleep apnea

M El-Chami, D Shaheen, B Ivers… - Journal of Applied …, 2015 - journals.physiology.org
We investigated if the number and duration of breathing events coupled to upper airway
collapsibility were affected by the time of day. Male participants with obstructive sleep apnea …