A systematic review and meta-analysis of clinical trials implementing aromatase inhibitors to treat male infertility

F Del Giudice, GM Busetto… - Asian journal of …, 2020 - journals.lww.com
Aromatase activity has commonly been associated with male infertility characterized by
testicular dysfunction with low serum testosterone and/or testosterone to estradiol ratio. In …

Clinical application of aromatase inhibitors to treat male infertility

C Yang, P Li, Z Li - Human Reproduction Update, 2022 - academic.oup.com
BACKGROUND Infertility affects 15% of men and contributes to nearly half of all cases of
infertility. Infertile men usually have impaired spermatogenesis, presenting as azoospermia …

Efficacy and safety of letrozole or anastrozole in the treatment of male infertility with low testosterone‐estradiol ratio: A meta‐analysis and systematic review

B Guo, J Li, Y Ma, Y Zhao, J Liu - Andrology, 2022 - Wiley Online Library
Abstract Background Aromatase inhibitors (AIs) have been used to treat male infertility for
decades. However, due to the lack of large‐scale randomized controlled studies and basic …

Aromatase inhibitors for female infertility: a systematic review of the literature

NP Polyzos, S Tzioras, AM Badawy, A Valachis… - Reproductive …, 2009 - Elsevier
Ovulation induction remains a milestone in the treatment of women with anovulatory
infertility. Clomiphene citrate (CC) is considered the first line treatment for induction of …

[PDF][PDF] Aromatase inhibitors in the treatment of oligozoospermic or azoospermic men: a systematic review of randomized controlled trials

MA Ribeiro, LF Gameiro, WR Scarano… - JBRA Assist …, 2016 - academia.edu
The aim of this study as to analyze published evidence regarding the effectiveness of
aromatase inhibitor therapy on improving spermatogenesis in infertile men. We carried out a …

Use of aromatase inhibitors in practice of gynecology

B Usluogullari, CZ Duvan, CA Usluogullari - Journal of ovarian research, 2015 - Springer
Purpose The conversion of androgens into estrogens by aromatase is called aromatization
and is inhibited by aromatase inhibitors (AIs). The aim of this article is to evaluate the use of …

Aromatase inhibitors for the treatment of infertility

MFM Mitwally, RF Casper - Expert Opinion on Investigational …, 2003 - Taylor & Francis
Ovarian stimulation during infertility treatment is used either alone or in conjunction with
intrauterine insemination and assisted reproductive technologies. At the present time, the …

[HTML][HTML] Aromatase inhibitors for male infertility

PN Schlegel - Fertility and sterility, 2012 - Elsevier
Some men with severely defective sperm production commonly have excess aromatase
activity, reflected by low serum testosterone and relatively elevated estradiol levels …

Aromatase inhibition for ovarian stimulation: future avenues for infertility management

MF Mitwally, RF Casper - Current Opinion in Obstetrics and …, 2002 - journals.lww.com
Ovarian stimulation is applied during infertility management either alone or in conjunction
with intrauterine insemination and assisted reproductive technologies. At the present time …

Do men with normal testosterone–oestradiol ratios benefit from letrozole for the treatment of male infertility?

L Shuling, MLS Kuei, SE Saffari, Z Jiayun… - Reproductive …, 2019 - Elsevier
Research question Previous studies of aromatase inhibitors on male infertility have focused
on men with low testosterone–oestradiol ratio of less than 10. Can aromatase inhibitors …