[HTML][HTML] Bacteria induce skin regeneration via IL-1β signaling

G Wang, E Sweren, H Liu, E Wier, MP Alphonse… - Cell host & …, 2021 - cell.com
Environmental factors that enhance regeneration are largely unknown. The immune system
and microbiome are attributed roles in repairing and regenerating structure but their precise …

Commensal microbiome promotes hair follicle regeneration by inducing keratinocyte HIF-1α signaling and glutamine metabolism

G Wang, E Sweren, W Andrews, Y Li, J Chen, Y Xue… - Science …, 2023 - science.org
Tissue injury induces metabolic changes in stem cells, which likely modulate regeneration.
Using a model of organ regeneration called wound-induced hair follicle neogenesis (WIHN) …

The cutaneous microbiome and wounds: new molecular targets to promote wound healing

TR Johnson, BI Gómez, MK McIntyre… - International journal of …, 2018 - mdpi.com
The ecological community of microorganisms in/on humans, termed the microbiome, is vital
for sustaining homeostasis. While culture-independent techniques have revealed the role of …

Oral antibiotic treatment induces skin microbiota dysbiosis and influences wound healing

M Zhang, Z Jiang, D Li, D Jiang, Y Wu, H Ren, H Peng… - Microbial ecology, 2015 - Springer
Antibiotic treatment eliminates commensal bacteria and impairs mucosal innate immune
defenses in the gut. However, whether oral antibiotic treatment could alter the composition of …

Microbiota and maintenance of skin barrier function

TA Harris-Tryon, EA Grice - Science, 2022 - science.org
Human skin forms a protective barrier against the external environment and is our first line of
defense against toxic, solar, and pathogenic insults. Our skin also defines our outward …

Skin microbiota and its interplay with wound healing

M Tomic-Canic, JL Burgess, KE O'Neill, N Strbo… - American journal of …, 2020 - Springer
The skin microbiota is intimately coupled with cutaneous health and disease. Interactions
between commensal microbiota and the multiple cell types involved in cutaneous wound …

The skin microbiome: current landscape and future opportunities

P Smythe, HN Wilkinson - International journal of molecular sciences, 2023 - mdpi.com
Our skin is the largest organ of the body, serving as an important barrier against the harsh
extrinsic environment. Alongside preventing desiccation, chemical damage and …

A mixed community of skin microbiome representatives influences cutaneous processes more than individual members

KH Loomis, SK Wu, A Ernlund, K Zudock, A Reno… - Microbiome, 2021 - Springer
Background Skin, the largest organ of the human body by weight, hosts a diversity of
microorganisms that can influence health. The microbial residents of the skin are now …

The wound microbiota: microbial mechanisms of impaired wound healing and infection

A Uberoi, A McCready-Vangi, EA Grice - Nature Reviews Microbiology, 2024 - nature.com
The skin barrier protects the human body from invasion by exogenous and pathogenic
microorganisms. A breach in this barrier exposes the underlying tissue to microbial …

Living in your skin: microbes, molecules, and mechanisms

MH Swaney, LR Kalan - Infection and immunity, 2021 - Am Soc Microbiol
Human skin functions as a physical, chemical, and immune barrier against the external
environment while also providing a protective niche for its resident microbiota, known as the …