[HTML][HTML] MiRNAs and piRNAs from bone marrow mesenchymal stem cell extracellular vesicles induce cell survival and inhibit cell differentiation of cord blood …
L De Luca, S Trino, I Laurenzana, V Simeon, G Calice… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Hematopoietic stem cells (HSC), including umbilical cord blood CD34+ stem cells (UCB-
CD34+), are used for the treatment of several diseases. Although different studies suggest …
CD34+), are used for the treatment of several diseases. Although different studies suggest …
Extracellular vesicle microRNA and protein cargo profiling in three clinical-grade stem cell products reveals key functional pathways
The cell origin-specific payloads within extracellular vesicles (EVs) mediate therapeutic
bioactivity for a wide variety of stem cell types. In this study, we profiled the microRNA …
bioactivity for a wide variety of stem cell types. In this study, we profiled the microRNA …
Osteoblasts secrete miRNA-containing extracellular vesicles that enhance expansion of human umbilical cord blood cells
J Morhayim, J Van De Peppel, E Braakman… - Scientific reports, 2016 - nature.com
Osteolineage cells represent one of the critical bone marrow niche components that support
maintenance of hematopoietic stem and progenitor cells (HSPCs). Recent studies …
maintenance of hematopoietic stem and progenitor cells (HSPCs). Recent studies …
Mesenchymal stem cell-derived extracellular vesicles affect disease outcomes via transfer of microRNAs
G Qiu, G Zheng, M Ge, J Wang, R Huang… - Stem Cell Research & …, 2018 - Springer
Mesenchymal stem cells (MSCs) are adult stromal cells with the capacity to differentiate into
multiple types of cells. MSCs represent an attractive option in regenerative medicine due to …
multiple types of cells. MSCs represent an attractive option in regenerative medicine due to …
[HTML][HTML] The effect of mesenchymal stem cell-derived extracellular vesicles on hematopoietic stem cells fate
H Timari, K Shamsasenjan… - Advanced …, 2017 - ncbi.nlm.nih.gov
Hematopoietic stem cells (HSCs) are multipotent stem cells, with self-renewal ability as well
as ability to generate all blood cells. Mesenchymal stem cells (MSCs) are multipotent stem …
as ability to generate all blood cells. Mesenchymal stem cells (MSCs) are multipotent stem …
Human umbilical cord mesenchymal stem cell-derived extracellular vesicles promote lung adenocarcinoma growth by transferring miR-410
L Dong, Y Pu, L Zhang, Q Qi, L Xu, W Li, C Wei… - Cell death & …, 2018 - nature.com
Although accumulating evidence has linked mesenchymal stem cells (MSCs) with tumor
growth, the underlying mechanisms are poorly understood. Here, we demonstrated for the …
growth, the underlying mechanisms are poorly understood. Here, we demonstrated for the …
Small non-coding RNA landscape of extracellular vesicles from human stem cells
S Kaur, AG Abu-Shahba, RO Paananen, H Hongisto… - Scientific reports, 2018 - nature.com
Extracellular vesicles (EVs) are reported to be involved in stem cell maintenance, self-
renewal, and differentiation. Due to their bioactive cargoes influencing cell fate and function …
renewal, and differentiation. Due to their bioactive cargoes influencing cell fate and function …
Mesenchymal stromal cell-derived extracellular vesicles: novel approach in hematopoietic stem cell transplantation
DP Sarvar, H Effatpanah, P Akbarzadehlaleh… - Stem Cell Research & …, 2022 - Springer
Bone marrow mesenchymal stromal cells (MSCs) play a crucial role in the regulation of
hematopoiesis. These cells affect the process through direct cell–cell contact, as well as …
hematopoiesis. These cells affect the process through direct cell–cell contact, as well as …
[HTML][HTML] Interferon-γ and hypoxia priming have limited effect on the miRNA landscape of human mesenchymal stromal cells-derived extracellular vesicles
Mesenchymal stromal cell (MSC)-based cell therapy has received great interest in
regenerative medicine. Priming the cells during the culture phase can improve their efficacy …
regenerative medicine. Priming the cells during the culture phase can improve their efficacy …
Preclinical experimental applications of miRNA loaded BMSC extracellular vesicles
Bone marrow mesenchymal stem cells have been investigated for many years, especially for
tissue regeneration, and have inherent limitations. One of the rapidly developing fields in the …
tissue regeneration, and have inherent limitations. One of the rapidly developing fields in the …
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