Is junk DNA bunk? A critique of ENCODE
WF Doolittle - Proceedings of the National Academy of …, 2013 - National Acad Sciences
Do data from the Encyclopedia Of DNA Elements (ENCODE) project render the notion of
junk DNA obsolete? Here, I review older arguments for junk grounded in the C-value …
junk DNA obsolete? Here, I review older arguments for junk grounded in the C-value …
Junk or functional DNA? ENCODE and the function controversy
In its last round of publications in September 2012, the Encyclopedia Of DNA Elements
(ENCODE) assigned a biochemical function to most of the human genome, which was taken …
(ENCODE) assigned a biochemical function to most of the human genome, which was taken …
The C-value paradox, junk DNA and ENCODE
SR Eddy - Current biology, 2012 - cell.com
You might expect more complex organisms to have progressively larger genomes, but
eukaryotic genome size fails to correlate well with apparent complexity, and instead varies …
eukaryotic genome size fails to correlate well with apparent complexity, and instead varies …
ENCODE project writes eulogy for junk DNA
E Pennisi - 2012 - science.org
This week, 30 research papers, including six in Nature and additional papers published
online by Science, sound the death knell for the idea that our DNA is mostly littered with …
online by Science, sound the death knell for the idea that our DNA is mostly littered with …
Decoding" coding": Information and DNA
S Sarkar - BioScience, 1996 - JSTOR
Following Crick (1958), the last pre-cept is usually called the" Central Dogma" of molecular
biology. These three precepts are so universally accepted that they usually find their way …
biology. These three precepts are so universally accepted that they usually find their way …
The genetic code.
I Asimov - 1964 - cabidigitallibrary.org
The nucleic acids have become fashionable and we shall presumably be offered
monographs on the subject for many years to come. Each author no doubt feels that his own …
monographs on the subject for many years to come. Each author no doubt feels that his own …
Coincidence, coevolution, or causation? DNA content, cell size, and the C-value enigma
TR Gregory - Biological reviews, 2001 - cambridge.org
Variation in DNA content has been largely ignored as a factor in evolution, particularly
following the advent of sequence-based approaches to genomic analysis. The significant …
following the advent of sequence-based approaches to genomic analysis. The significant …
Not junk after all
W Makalowski - Science, 2003 - science.org
From bacteria to mammals, the DNA content of genomes has increased by about three
orders of magnitude in just 3 billion years of evolution (1). Early DNA association studies …
orders of magnitude in just 3 billion years of evolution (1). Early DNA association studies …
Why so many noncoding nucleotides? The eukaryote genome as an epigenetic machine
E Zuckerkandl - Genetica, 2002 - Springer
It is recalled that dispensability of sequences and neutral substitution rate must not be
construed to be markers of nonfunctionality. Different aspects of functionality relate to …
construed to be markers of nonfunctionality. Different aspects of functionality relate to …