[HTML][HTML] Improved pharmacokinetic and lymphatic uptake of Rose Bengal after transfersome intradermal deposition using hollow microneedles
The lymphatic system is active in several processes that regulate human diseases, among
which cancer progression stands out. Thus, various drug delivery systems have been …
which cancer progression stands out. Thus, various drug delivery systems have been …
[HTML][HTML] Trilayer dissolving polymeric microneedle array loading Rose Bengal transfersomes as a novel adjuvant in early-stage cutaneous melanoma management
Melanoma remains a global concern, but current therapies present critical limitations
pointing out the urgent need for novel strategies. Among these, the cutaneous delivery of …
pointing out the urgent need for novel strategies. Among these, the cutaneous delivery of …
Improving dermal delivery of rose bengal by deformable lipid nanovesicles for topical treatment of melanoma
Cutaneous melanoma is one of the most aggressive and metastatic forms of skin cancer.
However, current therapeutic options present several limitations, and the annual death rate …
However, current therapeutic options present several limitations, and the annual death rate …
Nano-sized drug delivery systems for lymphatic delivery
The lymphatic system plays important roles for immune responses, spreading cancer cells or
viruses and disseminating infections. Thus, targeting drugs, such as anticancer …
viruses and disseminating infections. Thus, targeting drugs, such as anticancer …
Nano-sized drug carriers and key factors for lymphatic delivery
JH Choi, YB Lee - Journal of Pharmaceutical Investigation, 2010 - koreascience.kr
Specific diseases like cancer and acquired immune deficiency syndrome (AIDS) occur at
various organs including lymphatics and spread through lymphatic system. Thus, if …
various organs including lymphatics and spread through lymphatic system. Thus, if …
Enhanced transdermal lymphatic delivery of doxorubicin via hyaluronic acid based transfersomes/microneedle complex for tumor metastasis therapy
H Yang, X Wu, Z Zhou, X Chen, M Kong - International journal of biological …, 2019 - Elsevier
Tumor-draining lymph nodes (TDLN) are major metastatic sites for many solid tumor to
support tumor progression and metastasis. Lymphatic delivery is regarded as a desirable …
support tumor progression and metastasis. Lymphatic delivery is regarded as a desirable …
Nanocarriers based oral lymphatic drug targeting: Strategic bioavailability enhancement approaches
In dosage form design, drug delivery technology facing a major problem due to degradation
of the drug through the first-pass metabolism upon oral delivery. We can overcome this …
of the drug through the first-pass metabolism upon oral delivery. We can overcome this …
Dual stimuli-responsive nanocarriers via a facile batch emulsion method for controlled release of Rose Bengal
Stimuli-responsive nanocarriers (SRN) hold great potential as drug delivery systems due to
the ability to tune the release of the drugs by controlling the external stimuli. However, the …
the ability to tune the release of the drugs by controlling the external stimuli. However, the …
Bioactive-chylomicrons for oral lymphatic targeting of berberine chloride: Novel flow-blockage assay in tissue-based and caco-2 cell line models
MA Elsheikh, YSR Elnaggar, DY Otify… - Pharmaceutical …, 2018 - Springer
Purpose To develop novel bioactive-chylomicrons to solve oral delivery obstacles of
Berberine chloride and target the lymphatic system. Methods Berberine-loaded bioactive …
Berberine chloride and target the lymphatic system. Methods Berberine-loaded bioactive …
Nano lipid based carriers for lymphatic voyage of anti-cancer drugs: An insight into the in-vitro, ex-vivo, in-situ and in-vivo study models
Management of cancer by anti-cancer drugs through conventional approaches has
presented tough challenges in clinical settings due to non-selective distribution and low …
presented tough challenges in clinical settings due to non-selective distribution and low …