Bioinformatic analysis of the potential common pathogenic mechanisms for psoriasis and metabolic syndrome

Y Zhou, L Han, Z Wang, R Fang, Y Wan, Z Yang… - Inflammation, 2023 - Springer
The pathogeneses of psoriasis and metabolic syndrome are closely related; however, the
underlying biological mechanisms are yet to be clarified. A psoriasis training set was …

Integrated bioinformatic analysis of differentially expressed genes and signaling pathways in plaque psoriasis

YJ Zhang, YZ Sun, XH Gao… - Molecular medicine …, 2019 - spandidos-publications.com
Psoriasis is an immune‑mediated cutaneous disorder with a high incidence and prevalence.
Patients with psoriasis may experience irritation, pain and psychological problems. The …

Identification of candidate biomarkers and pathways associated with psoriasis using bioinformatics analysis

Y Luo, Y Luo, J Chang, Z Xiao, B Zhou - Hereditas, 2020 - Springer
Background The aim of this study was to identify the candidate biomarkers and pathways
associated with psoriasis. GSE13355 and GSE14905 were extracted from the Gene …

Bioinformatics and Systems Biology Approach to Identify the Pathogenetic Link Between Psoriasis and Cardiovascular Disease

L Shi, X Du, J Li, G Zhang - Clinical, Cosmetic and Investigational …, 2023 - Taylor & Francis
Objective This study aimed to identify hub genes and common pathways shared between
psoriasis and cardiovascular disease (CVD) using bioinformatics analysis and predict the …

Exploring the comorbidity mechanisms between psoriasis and obesity based on bioinformatics

C Gao, J Li - Skin Research and Technology, 2024 - Wiley Online Library
Background Psoriasis is a chronic, recurrent, immune‐mediated inflammatory skin disease
characterized by erythematous scaly lesions. Obesity is currently a major global health …

Exploring the molecular underpinning of psoriasis and its associated comorbidities through network approach: cross talks of genes and pathways

S Choudhary, NS Khan, R Verma, P Saxena, H Singh… - 3 Biotech, 2023 - Springer
Patients with psoriasis often complain of several linked disorders including autoimmune and
cardiometabolic diseases. Understanding of molecular link between psoriasis and …

Exploring the Pathogenesis of Psoriasis Complicated With Atherosclerosis via Microarray Data Analysis

W Su, Y Zhao, Y Wei, X Zhang, J Ji, S Yang - Frontiers in immunology, 2021 - frontiersin.org
Background Although more and more evidence has supported psoriasis is prone to
atherosclerosis, the common mechanism of its occurrence is still not fully elucidated. The …

Discovering novel biomarkers associated with the pathogenesis of psoriasis: Evidence from bioinformatic analysis

Y Yang, S Xie, W Jiang, S Tang… - International Journal of …, 2022 - Taylor & Francis
Objective This study aimed to investigate key biomarkers and their molecular pathogenesis
in psoriasis. Methods Differentially expressed genes (DEGs) of datasets (GSE13355 …

Comorbidities of psoriasis-exploring the links by network approach

S Sundarrajan, M Arumugam - PloS one, 2016 - journals.plos.org
Increasing epidemiological studies in patients with psoriasis report the frequent occurrence
of one or more associated disorders. Psoriasis is associated with multiple comorbidities …

[HTML][HTML] Identification of potential key molecules and signaling pathways for psoriasis based on weighted gene co-expression network analysis

X Shu, XX Chen, XD Kang, M Ran… - World Journal of …, 2022 - ncbi.nlm.nih.gov
BACKGROUND Psoriasis is a chronic inflammatory skin disease, the pathogenesis of which
is more complicated and often requires long-term treatment. In particular, moderate to …