Tick bites, IgE to galactose‐alpha‐1, 3‐galactose and urticarial or anaphylactic reactions to mammalian meat: The alpha‐gal syndrome

JM Wilson, L Erickson, M Levin, SM Ailsworth… - Allergy, 2024 - Wiley Online Library
The recent recognition of a syndrome of tick‐acquired mammalian meat allergy has
transformed the previously held view that mammalian meat is an uncommon allergen. The …

Alpha‐gal syndrome: An emerging cause of food and drug allergy

K Rutkowski, A Wagner, R Rutkowski… - Clinical & …, 2020 - Wiley Online Library
Alpha‐gal syndrome (AGS) describes a wide spectrum of hypersensitivity reactions
mediated by specific IgE to the α‐gal epitope (galactose‐α‐1, 3‐galactose) ubiquitously …

On the cause and consequences of IgE to galactose-α-1, 3-galactose: A report from the National Institute of Allergy and Infectious Diseases Workshop on …

TAE Platts-Mills, SP Commins, T Biedermann… - Journal of Allergy and …, 2020 - Elsevier
The mammalian meat allergy known as the “α-Gal syndrome” relates to IgE specific for
galactose-α-1, 3-galactose (α-Gal), an oligosaccharide that is present in cells and tissues of …

Mammalian meat allergy following a tick bite: a case report

WL Jackson - Oxford Medical Case Reports, 2018 - academic.oup.com
The alpha-gal allergy is an emerging IgE-mediated reaction against the galactose-alpha-1,
3-galactose carbohydrate found in mammalian meats. Patients with this condition will …

[HTML][HTML] Could chiggers be contributing to the prevalence of galactose-alpha-1, 3-galactose sensitization and mammalian meat allergy?

LP Stoltz, LM Cristiano, APG Dowling… - The journal of allergy …, 2019 - ncbi.nlm.nih.gov
It is now well recognized that IgE antibodies to galactose-alpha-1, 3-galactose (alpha-gal)
result in delayed anaphylaxis to mammalian meats, including beef, pork, and lamb, among …

Ascaris lumbricoides and ticks associated with sensitization to galactose α1, 3-galactose and elicitation of the alpha-gal syndrome

T Murangi, P Prakash, BP Moreira, W Basera… - Journal of Allergy and …, 2022 - Elsevier
Background IgE to galactose alpha-1, 3 galactose (alpha-gal) causes alpha-gal syndrome
(delayed anaphylaxis after ingestion of mammalian meat). Development of sensitization has …

Delayed anaphylaxis to red meat associated with specific IgE antibodies to galactose

L Wen, J Zhou, J Yin, J Sun, Y Sun… - Allergy, Asthma & …, 2015 - synapse.koreamed.org
A novel delayed anaphylactic reaction to red meat, associated with tick bites and IgE
antibodies against galactose-α-1, 3-galactose (α-gal), was reported in 2009 in the US …

Discovery of alpha-gal-containing antigens in North American tick species believed to induce red meat allergy

G Crispell, SP Commins, SA Archer-Hartman… - Frontiers in …, 2019 - frontiersin.org
Development of specific IgE antibodies to the oligosaccharide galactose-α-1, 3-galactose (α-
gal) following tick bites has been shown to be the source of red meat allergy. In this study …

High levels of alpha-gal with large variation in the salivary glands of lone star ticks fed on human blood

LP Maldonado-Ruiz, KE Reif, A Ghosh, S Foré… - Scientific Reports, 2023 - nature.com
Tick bites, associated with the secretion of tick saliva containing the xenoglycan galactose-
alpha-1, 3-galactose (alpha-gal or aGal), are recognized as the causal factors of alpha-Gal …

Role and mechanism of galactose-alpha-1, 3-galactose in the elicitation of delayed anaphylactic reactions to red meat

C Hilger, J Fischer, F Wölbing… - Current allergy and asthma …, 2019 - Springer
Abstract Purpose of Review The alpha-Gal (α-Gal) syndrome is characterized by the
presence of IgE antibodies directed at the carbohydrate galactose-alpha-1, 3-galactose (α …