The role of tumor‐associated macrophages in hepatocellular carcinoma progression: A narrative review

X Zhang, C Yu, S Zhao, M Wang, L Shang… - Cancer …, 2023 - Wiley Online Library
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in the world,
with complex etiology and mechanism, and a high mortality rate. Tumor‐associated …

[HTML][HTML] Tumor-associated macrophages in hepatocellular carcinoma: friend or foe?

D Zhou, J Luan, C Huang, J Li - Gut and Liver, 2021 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide, and it
has diverse etiologies with multiple mechanisms. The diagnosis of HCC typically occurs at …

Tumor-associated macrophages in hepatocellular carcinoma pathogenesis, prognosis and therapy

K Arvanitakis, T Koletsa, I Mitroulis, G Germanidis - Cancers, 2022 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) constitutes a major health burden,
accounting for> 80% of primary liver cancers globally. Inflammation has come into the …

Macrophages as targets in hepatocellular carcinoma therapy

Y Liu, Z Mao, Y Ding, W Wang - Molecular Cancer Therapeutics, 2024 - AACR
Hepatocellular carcinoma (HCC) is a malignant tumor with a complex and diverse
immunosuppressive microenvironment. Tumor-associated macrophages (TAMs) are an …

Targeting the Heterogeneous Tumour-Associated Macrophages in Hepatocellular Carcinoma

A Agirre-Lizaso, M Huici-Izagirre… - Cancers, 2023 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is a highly lethal disease with an
increasing incidence. Despite the advancements in diagnosis and recent therapeutic …

Mechanisms of tumor-associated macrophages affecting the progression of hepatocellular carcinoma

Y Yuan, D Wu, J Li, D Huang, Y Zhao, T Gao… - Frontiers in …, 2023 - frontiersin.org
Tumor-associated macrophages (TAMs) are essential components of the immune cell
stroma of hepatocellular carcinoma. TAMs originate from monocytic myeloid-derived …

Macrophages orchestrate the liver Tumor Microenvironment

V Quaranta, C Ballarò, G Giannelli - Cancers, 2024 - mdpi.com
Simple Summary Liver cancer is a deadly disease, in which hepatocellular carcinoma and
cholangiocarcinoma are the most common types. Despite numerous advances, treatment …

[HTML][HTML] Crosstalk between tumor-associated macrophages and neighboring cells in hepatocellular carcinoma

PS Sung - Clinical and Molecular Hepatology, 2022 - ncbi.nlm.nih.gov
The tumor microenvironment generally shows a substantial immunosuppressive activity in
hepatocellular carcinoma (HCC), accounting for the suboptimal efficacy of immune-based …

Preclinical and clinical therapeutic strategies affecting tumor‐associated macrophages in hepatocellular carcinoma

H Degroote, A Van Dierendonck… - Journal of …, 2018 - Wiley Online Library
Hepatocellular carcinoma (HCC) most often develops in patients with underlying liver
disease characterized by chronic nonresolving inflammation. Tumor‐associated …

Targeting tumor associated macrophages in hepatocellular carcinoma

W Xu, Y Cheng, Y Guo, W Yao, H Qian - Biochemical pharmacology, 2022 - Elsevier
Hepatocellular carcinoma (HCC) contains numerous immune cell stroma, which constitutes
the tumor microenvironment (TME). Tumor-associated macrophages (TAMs) represent the …