As IGF-1 is the major factor that affects bone growth, and both osteocalcin and bone-specific
alkaline phosphatase are important markers of bone formation during puberty, there must be …

Background: Little is known about the changes in calciotropic hormones during puberty and
their relationship to bone mass during this critical period for skeletal accretion. Objectives …

A better understanding of how bone growth is regulated during peripuberty is important for
optimizing the attainment of peak bone mass and for the prevention of osteoporosis in later …

Context There is evidence to suggest that IGF-I plays a role in regulating bone turnover.
Objective To evaluate the relationships between serum concentrations of IGF-I and IGF …

Insulin-like growth factor 1 (IGF-1) is the major factor that affects linear bone growth. Also,
androgens and estrogens are necessary for increasing longitudinal bone growth during …

In this study we evaluated the role of cytokines and insulin-like growth factor (IGF) system in
mediating the skeletal changes that occur during puberty by determining the relationship …

Background Puberty is characterized by increases in growth hormone (GH) and insulin‐like
growth factor‐1 (IGF‐1) and the pubertal growth spurt. Bone formation and resorption also …

Summary objective During puberty, bone growth and mineralization as well as bone
turnover increase dramatically. The relation between height velocity and bone turnover is …

Objectives Intense physical activity in peripubertal girls may delay menarche and cause
menstrual disorders and estrogen deficiency, particularly in sport disciplines that require …

The dramatic bone growth during puberty encompasses three distinct but integrated
processes: accelerated linear growth, bone maturation, and rapid acquisition of bone mass …