Machine learning applications for multi-scale computed tomography of skeletal tissues

S Rytky - 2023 - oulurepo.oulu.fi
Osteoarthritis (OA) is a serious joint disease affecting millions of people globally. Early
detection of the disease allows for slowing down its progression, leading to reduced …

Clinical super-resolution computed tomography of bone microstructure: application in musculoskeletal and dental imaging

SJO Rytky, A Tiulpin, MAJ Finnilä, SS Karhula… - Annals of Biomedical …, 2024 - Springer
Purpose Clinical cone-beam computed tomography (CBCT) devices are limited to imaging
features of half a millimeter in size and cannot quantify the tissue microstructure. We …

Automated analysis of rabbit knee calcified cartilage morphology using micro‐computed tomography and deep learning

SJO Rytky, L Huang, P Tanska, A Tiulpin… - Journal of …, 2021 - Wiley Online Library
Structural dynamics of calcified cartilage (CC) are poorly understood. Conventionally, CC
structure is analyzed using histological sections. Micro‐computed tomography (µCT) allows …

[HTML][HTML] Automating three-dimensional osteoarthritis histopathological grading of human osteochondral tissue using machine learning on contrast-enhanced micro …

SJO Rytky, A Tiulpin, T Frondelius, MAJ Finnilä… - Osteoarthritis and …, 2020 - Elsevier
Objective To develop and validate a machine learning (ML) approach for automatic three-
dimensional (3D) histopathological grading of osteochondral samples imaged with contrast …

Deep-learning for tidemark segmentation in human osteochondral tissues imaged with micro-computed tomography

A Tiulpin, M Finnilä, P Lehenkari, HJ Nieminen… - … on Advanced Concepts …, 2020 - Springer
Abstract Three-dimensional (3D) semi-quantitative grading of pathological features in
articular cartilage (AC) offers significant improvements in basic research of osteoarthritis …

[HTML][HTML] A convolutional neural network-based method for the generation of super-resolution 3D models from clinical CT images

Y Zhou, E Klintström, B Klintström, SJ Ferguson… - Computer Methods and …, 2024 - Elsevier
Background and objective The accurate evaluation of bone mechanical properties is
essential for predicting fracture risk based on clinical computed tomography (CT) images …

A Super-Resolution Diffusion Model for Recovering Bone Microstructure from CT Images

TJ Chan, CS Rajapakse - Radiology: Artificial Intelligence, 2023 - pubs.rsna.org
Purpose To use a diffusion-based deep learning model to recover bone microstructure from
low-resolution images of the proximal femur, a common site of traumatic osteoporotic …

Deep learning-based segmentation from histology allows for automated quantification of calcified cartilage morphology in a rabbit model of post-traumatic …

SJ Rytky, L Huang, A Tiulpin, P Tanska… - Osteoarthritis and …, 2020 - oarsijournal.com
Purpose: Calcified cartilage (CC) undergoes constant remodeling due to two competing
events: 1) mineralization of the deep non-calcified cartilage that advances the tidemark, and …

Joint super-resolution/segmentation approaches for the tomographic images analysis of the bone micro-architecture

A Toma - 2016 - theses.hal.science
The investigation of trabecular bone micro-architecture provides relevant information to
determine the bone strength, an important parameter in osteoporosis investigation. While …

Utility of deep learning super‐resolution in the context of osteoarthritis MRI biomarkers

AS Chaudhari, KJ Stevens, JP Wood… - Journal of Magnetic …, 2020 - Wiley Online Library
Background Super‐resolution is an emerging method for enhancing MRI resolution;
however, its impact on image quality is still unknown. Purpose To evaluate MRI super …