Following its discovery more than 30 years ago, the enhanced permeability and retention
(EPR) effect has become the guiding principle for cancer nanomedicine development. Over …

The use of nanomedicine for cancer treatment takes advantage of its preferential
accumulation in tumors owing to the enhanced permeability and retention (EPR) effect. The …

Abstract The Enhanced Permeability and Retention (EPR) effect has been recognized as the
central paradigm in tumor-targeted delivery in the last decades. In the wake of this concept …

Editorial Huynh & Zheng tensive medication. While in some countries hyperten sion is not
prevalent, such as Japan where the current study was conducted, in other countries such as …

Tumor targeting by nanomedicine-based therapeutics has emerged as a promising
approach to overcome the lack of specificity of conventional chemotherapeutic agents and to …

The enhanced permeability and retention (EPR) effect constitutes the rationale by which
nanotechnologies selectively target drugs to tumors. Despite promising preclinical and …

Over the past three decades, the enhanced permeability and retention (EPR) effect has
been considered the basis of tumor-targeted drug delivery. Various cancer nanomedicines …

Enhanced permeability and retention (EPR) effect is a popular strategy for targeting
nanosize anticancer drugs to tumor tissues. In this review we discuss how EPR effect …

Cancer causes the second-highest rate of death world-wide. A major shortcoming inherent
in most of anticancer drugs is their lack of tumor selectivity. Nanodrugs for cancer therapy …

Starting with the enhanced permeability and retention (EPR) effect discovery, nanomedicine
has gained a crucial role in cancer treatment. The advances in the field have led to the …