Latest approaches for the treatment of obesity

VM Jackson, DM Breen, JP Fortin, A Liou… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: Obesity is a body weight disorder characterized by excess adiposity that
increases the risk for developing co-morbidities such as type 2 diabetes. A large medical …

Drug development strategies for the treatment of obesity: how to ensure efficacy, safety, and sustainable weight loss

S Barja-Fernandez, R Leis, FF Casanueva… - Drug Design …, 2014 - Taylor & Francis
The prevalence of obesity has increased worldwide, and approximately 25%–35% of the
adult population is obese in some countries. The excess of body fat is associated with …

Addressing the unmet medical need for safe and effective weight loss therapies

CM Arbeeny - Obesity research, 2004 - Wiley Online Library
Obesity is a significant healthcare problem worldwide and increases the risk of developing
debilitating diseases including type 2 diabetes, cardiovascular disease, and cancer …

New advances in models and strategies for developing anti-obesity drugs

GW Kim, JE Lin, ES Blomain… - Expert opinion on drug …, 2013 - Taylor & Francis
Introduction: Obesity is a worldwide pandemic. Obesity-related health and economic costs
are staggering. Existing strategies to combat obesity through lifestyle improvements and …

Future pharmacotherapy for obesity: new anti-obesity drugs on the horizon

G Srivastava, C Apovian - Current obesity reports, 2018 - Springer
Abstract Purpose of Review Obesity is a global health crisis with detrimental effects on all
organ systems leading to worsening disease state and rising costs of care. Persons with …

Anti-obesity therapies.

I Melnikova, D Wages - Nature Reviews Drug Discovery, 2006 - nature.com
Obesity is a common, serious and growing problem. Current epidemiological estimates
suggest that 1.1 billion people worldwide are above their ideal weight. In the US, 65% of …

Obesity pharmacotherapy: what is next?

F Colon-Gonzalez, GW Kim, JE Lin… - Molecular aspects of …, 2013 - Elsevier
The increase in obesity in the Unites States and around the world in the last decade is
overwhelming. The number of overweight adults in the world surpassed 1 billion in 2008 …

Obesity medications in development

CJ Rebello, FL Greenway - Expert opinion on investigational drugs, 2020 - Taylor & Francis
Introduction: Obesity is compounded by a neurobiology that is resistant to weight loss.
Therefore, the development of pharmacotherapies to address the pathology underlying the …

Pharmacotherapy for obesity: novel agents and paradigms

S Manning, A Pucci, N Finer - Therapeutic advances in …, 2014 - journals.sagepub.com
Public health initiatives focused on obesity prevention and lifestyle intervention programmes
for patients with obesity have struggled to contain the obesity epidemic to date. In recent …

Advances in physiology, design and development of novel medications changing the landscape of obesity pharmacotherapy

M Chakhtoura, CS Mantzoros - Metabolism-Clinical and …, 2023 - metabolismjournal.com
As the word has been celebrating innovations and technological achievements during the
last few decades, there has also been a noticeable increase in various non-communicable …