Sudden blastic transformation in treatment‐free remission chronic myeloid leukaemia.
M Alfayez, G Richard‐Carpentier… - British Journal of …, 2019 - search.ebscohost.com
This phase starts after discontinuation of TKI therapy, and is characterized by continued
remission with undetectable-or stable low detectable-disease by the most sensitive method …
remission with undetectable-or stable low detectable-disease by the most sensitive method …
Blastic transformation in chronic myelogenous leukemia: experience with 50 patients
SM Marks, R McCaffrey, DS Rosenthal… - Medical and …, 1978 - Wiley Online Library
Fifty consecutive patients with blastic chronic myelogenous leukemia were evaluated
clinically, morphologically, biochemically, and therapeutically. Forty‐five patients had a …
clinically, morphologically, biochemically, and therapeutically. Forty‐five patients had a …
[引用][C] The blastic crisis of chronic myeloid leukaemia: acute transformation of a preleukaemic condition?
B Pedersen - British Journal of Haematology, 1973 - Wiley Online Library
The characteristic course of chronic niyeloid leukaemia (CML) includes a relatively long
phase where, after non-intensive treatment, the patients remain in a clinical and …
phase where, after non-intensive treatment, the patients remain in a clinical and …
[引用][C] Current status of blastic transformation in chronic myelogenous leukemia
JC Barton, ME Conrad - American Journal of Hematology, 1978 - Wiley Online Library
Although chronic myelocytic leukemia (CML) represents only 15% of all cases of leukemia,
its maximal incidence occurs in the third to sixth decades of life such that individuals are …
its maximal incidence occurs in the third to sixth decades of life such that individuals are …
The pathogenesis and clinical patterns of blastic crisis of chronic myeloid leukemia.
DR Boggs - Seminars in Oncology, 1976 - europepmc.org
Blast crisis terminates the life of the majority (approximately 80%) of patients with CML. The
time of its onset appears to be a random phenomenon, varying from a probable coincidence …
time of its onset appears to be a random phenomenon, varying from a probable coincidence …
Relapse into blast crisis following bone marrow transplantation for chronic phase chronic myeloid leukaemia: a report of five cases
JO Cullis, DI Marks, AP Schwarer… - British journal of …, 1992 - Wiley Online Library
A proportion of patients receiving allogeneic bone marrow transplants (BMT) for chronic
myeloid leukaemia (CML) in first chronic phase relapse; most of these relapses show …
myeloid leukaemia (CML) in first chronic phase relapse; most of these relapses show …
Sudden onset of the blastic phase of chronic myelogenous leukemia: Patterns and implications
H Kantarjian, S O'Brien, J Cortes, F Giles, D Thomas… - Cancer, 2003 - Wiley Online Library
BACKGROUND Therapeutic options in Philadelphia chromosome‐positive chronic
myelogenous leukemia (Ph‐positive CML) in chronic phase include allogeneic stem cell …
myelogenous leukemia (Ph‐positive CML) in chronic phase include allogeneic stem cell …
Molecular evidence for the clonal origin of blast crisis in chronic myeloid leukaemia
JR Zalcberg, ML Friedlander, MD Minden - British journal of cancer, 1986 - nature.com
Cytogenetic and enzymatic studies have shown that chronic myeloid leukemia (CML)
represents the clonal proliferation of a pluripotent stem cell. The Philadelphia chromosome …
represents the clonal proliferation of a pluripotent stem cell. The Philadelphia chromosome …
Factors affecting duration of survival after onset of blastic transformation of chronic myeloid leukemia
We analyzed factors having an impact on response to treatment and survival in 78
consecutive patients with chronic myeloid leukemia (CML) in blastic transformation (BT) …
consecutive patients with chronic myeloid leukemia (CML) in blastic transformation (BT) …
Treatment free remission in chronic myeloid leukemia: Lights and shadows
In addition to the best possible overall survival, discontinuation of the tyrosine kinase-
inhibitor (TKI) treatment [treatment free remission (TFR)] without observing a recurrence of …
inhibitor (TKI) treatment [treatment free remission (TFR)] without observing a recurrence of …