Akt is a serine/threonine kinase and it participates in the key role of the PI3K signaling
pathway. The Akt can be activated by a wide range of growth signals and the biochemical …

Abstract AKT/protein kinase B (PKB) is a cardinal node in diverse signaling cascades
important in both normal cellular physiology and various disease states. AKT signaling …

Akt (protein kinase B) is a serine/threonine kinase which is a central regulator of widely
divergent cellular processes including proliferation, differentiation, migration, survival and …

Growth factor signaling plays a pivotal role in diverse biological functions, such as cell
growth, apoptosis, senescence, and migration and its deregulation has been linked to …

AKT (also known as PKB) plays a central role in a variety of cellular processes including cell
growth, motility and survival in both normal and tumor cells. The AKT pathway is also …

The PI 3-K signaling pathway has been the subject of intense investigation for over a
decade because it regulates a multitude of cellular processes. Deregulation of this pathway …

Since it's discovery as an effector of PI 3-K (phosphoinositide 3-kinase)(Franke et al., 1995),
the serine/threonine kinase Akt (also known as PKB, protein kinase B) has emerged as a …

The serine/threonine kinase Akt functions intracellularly as a cardinal nodal point for a
constellation of converging upstream signaling pathways, which involve stimulation of …

Akt (also known as PKB) signaling orchestrates many aspects of biological functions and,
importantly, its deregulation is linked to cancer development. Akt activity is well-known …

The serine/threonine kinase Akt/PKB pathway presents an exciting new target for molecular
therapeutics, as it functions as a cardinal nodal point for transducing extracellular (growth …