Transgenic animal mammary gland bioreactors are used to produce recombinant proteins.
However, it is difficult to validate whether these transgenic domestic animals are able to …

One major drawback in research of animal mammary gland bioreactors is the low production
rate of high-expressing transgenic animals due to position effects. To obtain high and stable …

In our previous study, using a bovine β-casein/human lactoferrin hybrid gene, transgenic
mice were generated to target the expression of human lactoferrin (hLF) into the mammary …

In our previous study, transgenic mice were generated that expressed human lactoferrin
(hLF) in milk using cDNA under control of the 2kb bovine ƒÀ-casein promoter. The …

Transgenic mice were developed which expressed human lactoferrin (hLF) in the mammary
gland. This was achieved by using regulatory elements of bovine β-casein gene, rabbit β …

Large-scale production of biopharmaceuticals by current bioreactor techniques is limited by
low transgenic efficiency and low expression of foreign proteins. In general, a bacterial …

It is very important to develop an effective, specific, and robust expression cassette that
ensures a high level of expression in the mammary glands. In this study, we designed and …

This review examines the expression of heterologous proteins in the milk of transgenic
animals. The expression of human lactoferrin in a mammary gland-specific expression …

The combination of somatic cell nuclear transfer (SCNT) and transgenic technology leads to
the production of transgenic cloned animals, wherein the preparation of competent …

The expression of human lactoferrin (hLF) in the milk of transgenic mice is described.
Regulatory sequences derived from the bovine αS1-casein gene were fused to the coding …