The first total synthesis of marine sesterterpenoid ansellone G (2) was accomplished. This
strategy utilizes the Prins cyclization reaction of a chloro-substituted homoallyl alcohol to …

The total synthesis and biological evaluation of the marine sesterterpenoid ansellone A (1),
an HIV latency-reversing agent, and its analogues are reported. The key to the success of …

Ansellane‐type sesterterpenoids including, ansellones A‐G and (+)‐phorbadione are
structurally novel marine secondary metabolites which exhibit anticancer and anti‐HIV …

Eight new sesterterpenoids, alotaketals D (8) and E (9), ansellones D (10), E (11), F (12),
and G (13), and anvilones A (14) and B (15), have been isolated from extracts of the marine …

Structurally simplified analogues of ansellone A, in which the decalin skeleton is replaced
with a lipophilic chain, were prepared and their HIV latency‐reversing activities biologically …

The formal synthesis of (+)-sorangicin A was completed by two independent routes. Both
approaches feature a cross metathesis reaction to form the C29–C30 bond to arrive at the …

A concise total synthesis of 7-desmethoxyfusarentin and its methyl ether has been
accomplished involving a sequence of reactions such as Prins cyclization, ring opening of …

Cascade reactions, in which the reactive intermediate from one step directly undergoes
further transformations, are important in organic synthesis because they can build up …

Conjugate addition of potassium cyanide to S-(+)-carvone followed by annulation with
methyl vinyl ketone nitrile 4 in high yield. Methylation of 4, removal of the isopropenyl group …

We have developed an efficient diastereoselective synthetic route towards a nardosinane
sesquiterpene scaffold. The strategy used a key bicyclic diene intermediate 11a, and …