The regulation of PBXs and their emerging role in cancer
Y Liu, X Ao, X Zhou, C Du… - Journal of Cellular and …, 2022 - Wiley Online Library
Pre‐B‐cell leukaemia transcription factor (PBX) proteins are a subfamily of evolutionarily
conserved, atypical homeodomain transcription factors that belong to the superfamily of …
conserved, atypical homeodomain transcription factors that belong to the superfamily of …
[HTML][HTML] PBX3 in Cancer
R Morgan, HS Pandha - Cancers, 2020 - mdpi.com
PBX3 is a homeodomain-containing transcription factor of the pre-B cell leukemia (PBX)
family, members of which have extensive roles in early development and some adult …
family, members of which have extensive roles in early development and some adult …
PBX1: a key character of the hallmarks of cancer
RN Veiga, JC de Oliveira, DF Gradia - Journal of Molecular Medicine, 2021 - Springer
Pre-B-cell leukemia homeobox transcription factor 1 (PBX1) was first identified as part of a
fusion protein resulting from the chromosomal translocation t (1; 19) in pre-B cell acute …
fusion protein resulting from the chromosomal translocation t (1; 19) in pre-B cell acute …
[HTML][HTML] Identification of PBX1 target genes in cancer cells by global mapping of PBX1 binding sites
PBX1 is a TALE homeodomain transcription factor involved in organogenesis and
tumorigenesis. Although it has been shown that ovarian, breast, and melanoma cancer cells …
tumorigenesis. Although it has been shown that ovarian, breast, and melanoma cancer cells …
[HTML][HTML] Targeting HOX/PBX dimers in cancer
R Morgan, M El-Tanani, KD Hunter, KJ Harrington… - Oncotarget, 2017 - ncbi.nlm.nih.gov
The HOX and PBX gene families encode transcription factors that have key roles in
establishing the identity of cells and tissues in early development. Over the last 20 years it …
establishing the identity of cells and tissues in early development. Over the last 20 years it …
PBX proteins: much more than Hox cofactors
A Laurent, R Bihan, F Omilli, S Deschamps… - International Journal of …, 2008 - hal.science
Pre-B cell leukaemia transcription factors (PBXs) were originally identified as Hox cofactors,
acting within transcriptional regulation complexes to regulate genetic programs during …
acting within transcriptional regulation complexes to regulate genetic programs during …
[HTML][HTML] PBX1 is a valuable prognostic biomarker for patients with breast cancer
X Ao, W Ding, H Ge, Y Zhang… - Experimental and …, 2020 - spandidos-publications.com
Pre-B-cell leukemia transcription factor (PBX) proteins have important roles in the
development of numerous organs. To date, four members of the PBX family have been …
development of numerous organs. To date, four members of the PBX family have been …
PBX3 is overexpressed in gastric cancer and regulates cell proliferation
Y Li, Z Sun, Z Zhu, J Zhang, X Sun, H Xu - Tumor Biology, 2014 - Springer
The pre-leukemia transcription factor 3 (PBX3) is a member of the PBX family of transcription
factors, which is known to increase DNA-binding/transcriptional activity of HOX proteins and …
factors, which is known to increase DNA-binding/transcriptional activity of HOX proteins and …
PBX3 is associated with proliferation and poor prognosis in patients with cervical cancer
H Li, G Sun, C Liu, J Wang, R Jing, J Wang… - OncoTargets and …, 2017 - Taylor & Francis
Pre-B-cell leukemia homeobox 3 (PBX3) is upregulated in various malignancies; however,
the role of PBX3 in cervical cancer (CC) is unknown. The purpose of this study was to …
the role of PBX3 in cervical cancer (CC) is unknown. The purpose of this study was to …
[PDF][PDF] Development of small molecule inhibitors targeting PBX1 transcription signaling as a novel cancer therapeutic strategy
PBX1 is a transcription factor involved in diverse cellular functions including organ
development, stem cell renewal, and tumorigenesis. PBX1 is localized at chr1q23. 3, a …
development, stem cell renewal, and tumorigenesis. PBX1 is localized at chr1q23. 3, a …