Atomoxetine modulates spontaneous and sensory-evoked discharge of locus coeruleus noradrenergic neurons

A Bari, G Aston-Jones - Neuropharmacology, 2013 - Elsevier
Atomoxetine (ATM) is a potent norepinephrine (NE) uptake inhibitor and increases both NE
and dopamine synaptic levels in prefrontal cortex, where it is thought to exert its beneficial …

Effect of the attention deficit/hyperactivity disorder drug atomoxetine on extracellular concentrations of norepinephrine and dopamine in several brain regions of the rat

CJ Swanson, KW Perry, S Koch-Krueger, J Katner… - …, 2006 - Elsevier
Atomoxetine is a selective inhibitor of norepinephrine transporters and is currently being
used in the pharmacotherapy of attention deficit/hyperactivity disorder (ADHD). We have …

Procholinergic and memory enhancing properties of the selective norepinephrine uptake inhibitor atomoxetine

ET Tzavara, FP Bymaster, CD Overshiner… - Molecular …, 2006 - nature.com
Atomoxetine has been approved by the FDA as the first new drug in 30 years for the
treatment of attention deficit/hyperactivity disorder (ADHD). As a selective norepinephrine …

Atomoxetine increases extracellular levels of norepinephrine and dopamine in prefrontal cortex of rat: a potential mechanism for efficacy in attention deficit …

FP Bymaster, JS Katner, DL Nelson… - …, 2002 - Elsevier
The selective norepinephrine (NE) transporter inhibitor atomoxetine (formerly called
tomoxetine or LY139603) has been shown to alleviate symptoms in Attention …

Atomoxetine reverses attentional deficits produced by noradrenergic deafferentation of medial prefrontal cortex

LA Newman, J Darling, J McGaughy - Psychopharmacology, 2008 - Springer
Background The majority of studies assessing executive function in attention deficit disorder
(ADD) have shown deficits in attentional set shifting using either the Wisconsin card sorting …

Atomoxetine improved response inhibition in adults with attention deficit/hyperactivity disorder

SR Chamberlain, N Del Campo, J Dowson, U Müller… - Biological …, 2007 - Elsevier
BACKGROUND: Atomoxetine, a highly selective noradrenaline reuptake inhibitor (SNRI),
shows efficacy in the treatment of attention-deficit/hyperactivity disorder (ADHD). Compared …

Atomoxetine: a review of its use in adults with attention deficit hyperactivity disorder

D Simpson, GL Plosker - Drugs, 2004 - Springer
Atomoxetine (Strattera™) is a selective norepinephrine reuptake inhibitor and nonstimulant
that has shown greater efficacy than placebo in attention deficit hyperactivity disorder …

Atomoxetine modulates right inferior frontal activation during inhibitory control: a pharmacological functional magnetic resonance imaging study

SR Chamberlain, A Hampshire, U Müller, K Rubia… - Biological …, 2009 - Elsevier
BACKGROUND: Atomoxetine, a selective noradrenaline reuptake inhibitor (SNRI) licensed
for the treatment of attention-deficit/hyperactivity disorder (ADHD), has been shown to …

Atomoxetine acts as an NMDA receptor blocker in clinically relevant concentrations

AG Ludolph, PT Udvardi, U Schaz… - British journal of …, 2010 - Wiley Online Library
Background and purpose: There is increasing evidence that not only the monoaminergic but
also the glutamatergic system is involved in the pathophysiology of attention‐deficit …

Atomoxetine affects transcription/translation of the NMDA receptor and the norepinephrine transporter in the rat brain–an in vivo study

PT Udvardi, KJ Föhr, C Henes, S Liebau… - Drug design …, 2013 - Taylor & Francis
Attention-deficit/hyperactivity disorder (ADHD) is the most frequently diagnosed
neurodevelopmental disorder. The norepinephrine transporter (NET) inhibitor atomoxetine …