[HTML][HTML] Probiotic supplementation and associated infant gut microbiome and health: a cautionary retrospective clinical comparison

C Quin, M Estaki, DM Vollman, JA Barnett, SK Gill… - Scientific reports, 2018 - nature.com
While probiotics are a multi-billion dollar industry, there is little evidence to show that
supplementing infants provides any health benefits. We conducted an observational study …

[HTML][HTML] Administration of two probiotic strains during early childhood does not affect the endogenous gut microbiota composition despite probiotic proliferation

MF Laursen, RP Laursen, A Larnkjær, KF Michaelsen… - BMC microbiology, 2017 - Springer
Background Probiotics are increasingly applied to prevent and treat a range of infectious,
immune related and gastrointestinal diseases. Despite this, the mechanisms behind the …

Routine use of probiotics in preterm infants: longitudinal impact on the microbiome and metabolome

B Abdulkadir, A Nelson, T Skeath, ECL Marrs, JD Perry… - Neonatology, 2016 - karger.com
Background: Probiotics are live microbial supplements that colonize the gut and potentially
exert health benefit to the host. Objectives: We aimed to determine the impact of a probiotic …

[PDF][PDF] Prebiotics in the infant microbiome: The past, present, and future

M Miqdady, J Al Mistarihi, A Azaz… - … Hepatology & Nutrition, 2020 - synapse.koreamed.org
The latest definition of a prebiotic is “a substrate that is selectively utilized by host
microorganisms conferring a health benefit”; it now includes non-food elements and is …

Probiotic intervention in the first months of life: short-term effects on gastrointestinal symptoms and long-term effects on gut microbiota

M Rinne, M Kalliomäki, S Salminen… - Journal of pediatric …, 2006 - journals.lww.com
Objectives: To determine whether probiotics administered for 6 months postnatally affect
gastrointestinal symptoms, crying and the compositional development of the gut microbiota …

Influence of probiotic supplementation on the developing microbiota in human preterm neonates

N Van Best, S Trepels-Kottek, P Savelkoul… - Gut …, 2020 - Taylor & Francis
Background Oral administration of probiotic bacteria to preterm neonates has been
recommended to prevent the development of necrotizing enterocolitis (NEC). The influence …

[HTML][HTML] Early probiotic supplementation with B. infantis in breastfed infants leads to persistent colonization at 1 year

CE O'Brien, AK Meier, K Cernioglo, RD Mitchell… - Pediatric …, 2022 - nature.com
Background Recent studies have reported a dysfunctional gut microbiome in breastfed
infants. Probiotics have been used in an attempt to restore the gut microbiome; however …

The effect of early probiotic exposure on the preterm infant gut microbiome development

Y Hui, B Smith, MS Mortensen, L Krych… - Gut …, 2021 - Taylor & Francis
Premature birth, especially if born before week 32 of gestation, is associated with increased
risk of neonatal morbidity and mortality. Prophylactic use of probiotics has been suggested …

Probiotics to improve the gut microbiome in premature infants: are we there yet?

EM Mercer, MC Arrieta - Gut microbes, 2023 - Taylor & Francis
Gut microbiome maturation in infants born prematurely is uniquely influenced by the
physiological, clinical, and environmental factors surrounding preterm birth and early life …

[HTML][HTML] The preterm gut microbiota and administration routes of different probiotics: a randomized controlled trial

EN Rahkola, S Rautava, H Hiltunen, C Ross… - Pediatric …, 2023 - nature.com
Background Preterm children with their aberrant gut microbiota and susceptibility to
infections and inflammation constitute a considerable target group for probiotic therapy to …