Objective To determine whether moderate hypothermia after hypoxic-ischaemic
encephalopathy in neonates improves survival and neurological outcome at 18 months of …

Background Newborn animal studies and pilot studies in humans suggest that mild
hypothermia following peripartum hypoxia‐ischaemia in newborn infants may reduce …

Objective To establish the evidence of therapeutic hypothermia for newborns with hypoxic
ischemic encephalopathy (HIE). Data Sources Cochrane Central Register of Controlled …

Background The objective of this study was to systematically review randomized trials
assessing therapeutic hypothermia as a treatment for term neonates with hypoxic ischemic …

Importance Hypothermia initiated at less than 6 hours after birth reduces death or disability
for infants with hypoxic-ischemic encephalopathy at 36 weeks' or later gestation. To our …

Objectives To systematically review the effectiveness, as determined by survival without
moderate to severe neurodevelopmental disability in infancy and childhood, and the safety …

Objectives To examine if therapeutic hypothermia reduces the composite outcome of death,
moderate or severe disability at 18 months or more after mild neonatal encephalopathy …

Background Hypoxic perinatal brain injury is caused by lack of oxygen to baby's brain and
can lead to death or permanent brain damage. However, the effectiveness of therapeutic …

Background Moderate hypothermia in neonates with hypoxic–ischaemic encephalopathy
might improve survival and neurological outcomes at up to 18 months of age, although …

Background Cerebral hypothermia can improve outcome of experimental perinatal hypoxia-
ischaemia. We did a multicentre randomised controlled trial to find out if delayed head …