Data from the World Health Organization (National Institute on Aging,) and the National
Institutes of Health (He et al.,) predicts that while today the worldwide population over 65 …

Sporadic or idiopathic Parkinson's disease (PD) is an age-related neurodegenerative
disorder of unknown origin that ranks only second behind Alzheimer's disease (AD) in …

Since the 1960's treatments for Parkinson's disease (PD) have traditionally been directed to
restore or replace dopamine, with L-Dopa being the gold standard. However, chronic L …

Since the first formal description of Parkinson disease (PD) two centuries ago, our
understanding of this common neurodegenerative disorder has expanded at all levels of …

After Alzheimer's disease, Parkinson's disease (PD) is the second most prevalent and
incidental neurodegenerative disorder, affecting more than 2% of the population older than …

Background: Parkinson's disease is a common disorder that becomes more prevalent with
advanced age. The cardinal features are related to dopamine deficiency, arising from loss of …

Parkinson's disease (PD) is the second-leading cause of dementia and is characterized by a
progressive loss of dopaminergic neurons in the substantia nigra alongside the presence of …

Parkinson's disease is the second most common neurodegenerative disorder and, at
present, has no cure. Both environmental and genetic factors have been implicated in the …

Parkinson's disease (PD) is the second most common neurodegenerative disease
worldwide. Since its first description as a neurological disorder by James Parkinson (1755 …

Although idiopathic Parkinson disease (PD) remains the only neurodegenerative disorder
for which there are highly effective symptomatic therapies, there are still major unmet needs …