Whole-genome mapping of epigenetic modification of 5-formylcytosine at single-base resolution by chemical labeling enrichment and deamination sequencing
JH Ding, G Li, J Xiong, FL Liu, NB Xie, TT Ji… - Analytical …, 2024 - ACS Publications
DNA cytosine methylation (5-methylcytosine, 5mC) is a predominant epigenetic modification
that plays a critical role in a variety of biological and pathological processes in mammals. In …
that plays a critical role in a variety of biological and pathological processes in mammals. In …
Bisulfite-free, base-resolution analysis of 5-formylcytosine at the genome scale
Active DNA demethylation in mammals involves oxidation of 5-methylcytosine (5mC) to 5-
hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC) …
hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC) …
Sensitive and simultaneous determination of 5-methylcytosine and its oxidation products in genomic DNA by chemical derivatization coupled with liquid …
Cytosine methylation (5-methylcytosine, 5-mC) in genomic DNA is an important epigenetic
mark that has regulatory roles in diverse biological processes. 5-mC can be oxidized …
mark that has regulatory roles in diverse biological processes. 5-mC can be oxidized …
Base-resolution maps of 5-formylcytosine and 5-carboxylcytosine reveal genome-wide DNA demethylation dynamics
The TET family of dioxygenases can oxidize 5-methylcytosine (5mC) to 5-
hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC) in …
hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC) in …
Jump-seq: genome-wide capture and amplification of 5-hydroxymethylcytosine sites
5-Hydroxymethylcytosine (5hmC) arises from the oxidation of 5-methylcytosine (5mC) by
Fe2+ and 2-oxoglutarate-dependent 10–11 translocation (TET) family proteins. Substantial …
Fe2+ and 2-oxoglutarate-dependent 10–11 translocation (TET) family proteins. Substantial …
Single-base resolution analysis of 5-formyl and 5-carboxyl cytosine reveals promoter DNA methylation dynamics
Ten eleven translocation (Tet) proteins oxidize 5-methylcytosine (5mC) to 5-
hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC). 5fC …
hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-carboxylcytosine (5caC). 5fC …
Nucleic acid modifications with epigenetic significance
Epigenetic modifications influence gene expression without alterations to the underlying
nucleic acid sequence. In addition to the well-known 5-methylcytosine (5mC), 5 …
nucleic acid sequence. In addition to the well-known 5-methylcytosine (5mC), 5 …
Genome-wide distribution of 5-formylcytosine in embryonic stem cells is associated with transcription and depends on thymine DNA glycosylase
Background Methylation of cytosine in DNA (5mC) is an important epigenetic mark that is
involved in the regulation of genome function. During early embryonic development in …
involved in the regulation of genome function. During early embryonic development in …
Comprehensive evaluation of genome-wide 5-hydroxymethylcytosine profiling approaches in human DNA
Background The discovery that 5-methylcytosine (5mC) can be oxidized to 5-
hydroxymethylcytosine (5hmC) by the ten-eleven translocation (TET) proteins has prompted …
hydroxymethylcytosine (5hmC) by the ten-eleven translocation (TET) proteins has prompted …
Methylation-assisted bisulfite sequencing to simultaneously map 5fC and 5caC on a genome-wide scale for DNA demethylation analysis
F Neri, D Incarnato, A Krepelova, C Parlato… - Nature protocols, 2016 - nature.com
Active DNA demethylation is mediated by ten-eleven translocation (TET) proteins that
progressively oxidize 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), 5 …
progressively oxidize 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC), 5 …