In Vitro Activity of Sulbactam-Durlobactam against Global Isolates of Acinetobacter baumannii-calcoaceticus Complex Collected from 2016 to 2021
JA Karlowsky, MA Hackel, SM McLeod… - Antimicrobial Agents …, 2022 - Am Soc Microbiol
Sulbactam-durlobactam is a β-lactam-β-lactamase inhibitor combination designed to treat
serious Acinetobacter baumannii-calcoaceticus complex (ABC) infections, including …
serious Acinetobacter baumannii-calcoaceticus complex (ABC) infections, including …
In Vitro Activity of Sulbactam-Durlobactam against Acinetobacter baumannii-calcoaceticus Complex Isolates Collected Globally in 2016 and 2017
SM McLeod, SH Moussa, MA Hackel… - Antimicrobial Agents …, 2020 - Am Soc Microbiol
Acinetobacter baumannii-calcoaceticus complex (ABC) organisms cause severe infections
that are difficult to treat due to preexisting antibiotic resistance. Sulbactam-durlobactam …
that are difficult to treat due to preexisting antibiotic resistance. Sulbactam-durlobactam …
Molecular drivers of resistance to sulbactam-durlobactam in contemporary clinical isolates of Acinetobacter baumannii
SH Moussa, AB Shapiro, SM McLeod… - Antimicrobial Agents …, 2023 - Am Soc Microbiol
Acinetobacter baumannii-calcoaceticus complex (ABC) causes severe infections that are
difficult to treat due to pre-existing antibiotic resistance. Sulbactam-durlobactam (SUL-DUR) …
difficult to treat due to pre-existing antibiotic resistance. Sulbactam-durlobactam (SUL-DUR) …
[HTML][HTML] Activity of Sulbactam-Durlobactam and Comparators Against a National Collection of Carbapenem-Resistant Acinetobacter baumannii Isolates From Greece
D Petropoulou, M Siopi, S Vourli… - Frontiers in Cellular and …, 2022 - frontiersin.org
Background Acinetobacter baumannii is a leading cause of healthcare-associated infections
worldwide, due to both its persistence in the hospital setting and ability to acquire high levels …
worldwide, due to both its persistence in the hospital setting and ability to acquire high levels …
Efficacy and safety of sulbactam–durlobactam versus colistin for the treatment of patients with serious infections caused by Acinetobacter baumannii–calcoaceticus …
KS Kaye, AF Shorr, RG Wunderink, B Du… - The Lancet Infectious …, 2023 - thelancet.com
Background An urgent need exists for antibiotics to treat infections caused by carbapenem-
resistant Acinetobacter baumannii–calcoaceticus complex (ABC). Sulbactam–durlobactam …
resistant Acinetobacter baumannii–calcoaceticus complex (ABC). Sulbactam–durlobactam …
In vitro activity of sulbactam/durlobactam against global isolates of carbapenem-resistant Acinetobacter baumannii
H Seifert, C Müller, D Stefanik… - Journal of …, 2020 - academic.oup.com
Objectives To evaluate the activity of the novel broad-spectrum serine β-lactamase inhibitor
durlobactam (ETX2514) combined with sulbactam against global isolates of carbapenem …
durlobactam (ETX2514) combined with sulbactam against global isolates of carbapenem …
Sulbactam/durlobactam: first approval
SJ Keam - Drugs, 2023 - Springer
Abstract Sulbactam/durlobactam (XACDURO®), is a co-packaged antibacterial product that
has been developed by Entasis Therapeutics Inc. for the treatment of infections caused by …
has been developed by Entasis Therapeutics Inc. for the treatment of infections caused by …
The pharmacokinetics/pharmacodynamic relationship of durlobactam in combination with sulbactam in in vitro and in vivo infection model systems versus …
JP O'Donnell, SM Bhavnani - Clinical Infectious Diseases, 2023 - academic.oup.com
Sulbactam-durlobactam is a β-lactam/β-lactamase inhibitor combination currently in
development for the treatment of infections caused by Acinetobacter, including multidrug …
development for the treatment of infections caused by Acinetobacter, including multidrug …
[HTML][HTML] In vitro activity of sulbactam-durlobactam against carbapenem-resistant Acinetobacter baumannii and mechanisms of resistance
J Findlay, L Poirel, M Bouvier, P Nordmann - Journal of Global …, 2022 - Elsevier
ABSTRACT Objectives Multidrug-resistant Acinetobacter baumannii (MDR-Ab), particularly
strains producing oxacillinase (OXA)-type carbapenemases, have rapidly emerged in health …
strains producing oxacillinase (OXA)-type carbapenemases, have rapidly emerged in health …
Navigating Available Treatment Options for Carbapenem-Resistant Acinetobacter baumannii-calcoaceticus Complex Infections
RK Shields, DL Paterson… - Clinical Infectious …, 2023 - academic.oup.com
Carbapenem-resistant Acinetobacter baumannii-calcoaceticus complex (CRAB) is one of
the top-priority pathogens for new antibiotic development. Unlike other antibiotic-resistant …
the top-priority pathogens for new antibiotic development. Unlike other antibiotic-resistant …
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