Time series community genomics analysis reveals rapid shifts in bacterial species, strains, and phage during infant gut colonization

I Sharon, MJ Morowitz, BC Thomas… - Genome …, 2013 - genome.cshlp.org
The gastrointestinal microbiome undergoes shifts in species and strain abundances, yet
dynamics involving closely related microorganisms remain largely unknown because most …

Rapid evolution and strain turnover in the infant gut microbiome

DW Chen, NR Garud - Genome Research, 2022 - genome.cshlp.org
Although the ecological dynamics of the infant gut microbiome have been intensely studied,
relatively little is known about evolutionary dynamics in the infant gut microbiome. Here we …

Comparative analysis of 16S rRNA gene and metagenome sequencing in pediatric gut microbiomes

D Peterson, KS Bonham, S Rowland… - Frontiers in …, 2021 - frontiersin.org
The colonization of the human gut microbiome begins at birth, and over time, these microbial
communities become increasingly complex. Most of what we currently know about the …

Strain-resolved community genomic analysis of gut microbial colonization in a premature infant

MJ Morowitz, VJ Denef, EK Costello… - Proceedings of the …, 2011 - National Acad Sciences
The intestinal microbiome is a critical determinant of human health. Alterations in its
composition have been correlated with chronic disorders, such as obesity and inflammatory …

Identical bacterial populations colonize premature infant gut, skin, and oral microbiomes and exhibit different in situ growth rates

MR Olm, CT Brown, B Brooks, B Firek, R Baker… - Genome …, 2017 - genome.cshlp.org
The initial microbiome impacts the health and future development of premature infants.
Methodological limitations have led to gaps in our understanding of the habitat range and …

Succession of microbial consortia in the developing infant gut microbiome

JE Koenig, A Spor, N Scalfone… - Proceedings of the …, 2011 - National Acad Sciences
The colonization process of the infant gut microbiome has been called chaotic, but this view
could reflect insufficient documentation of the factors affecting the microbiome. We …

A compendium of 32,277 metagenome-assembled genomes and over 80 million genes from the early-life human gut microbiome

S Zeng, D Patangia, A Almeida, Z Zhou, D Mu… - Nature …, 2022 - nature.com
Age-specific reference genomes of the human gut microbiome can provide higher resolution
for metagenomic analyses including taxonomic classification, strain-level genomic …

Beyond bacteria: a study of the enteric microbial consortium in extremely low birth weight infants

MS LaTuga, JC Ellis, CM Cotton, RN Goldberg… - PloS one, 2011 - journals.plos.org
Extremely low birth weight (ELBW) infants have high morbidity and mortality, frequently due
to invasive infections from bacteria, fungi, and viruses. The microbial communities present in …

Natural history of the infant gut microbiome and impact of antibiotic treatment on bacterial strain diversity and stability

M Yassour, T Vatanen, H Siljander… - Science translational …, 2016 - science.org
The gut microbial community is dynamic during the first 3 years of life, before stabilizing to
an adult-like state. However, little is known about the impact of environmental factors on the …

Selective maternal seeding and environment shape the human gut microbiome

K Korpela, P Costea, LP Coelho… - Genome …, 2018 - genome.cshlp.org
Vertical transmission of bacteria from mother to infant at birth is postulated to initiate a life-
long host-microbe symbiosis, playing an important role in early infant development …