Determinants of bone mineral density in obese premenopausal women

MA Bredella, M Torriani, RH Ghomi, BJ Thomas… - Bone, 2011 - Elsevier
Despite being a risk factor for cardiovascular disease and diabetes mellitus, obesity has
been thought to protect against osteoporosis. However, recent studies have demonstrated a …

The differential relationship between fat mass and bone mineral density by gender and menopausal status

HJ Yoo, MS Park, SJ Yang, TN Kim, KI Lim… - Journal of bone and …, 2012 - Springer
Osteoporosis and obesity are important public health problems in an aging society. We
investigated the differential impacts of fat on bone mineral density (BMD) according to …

Vertebral bone marrow fat is positively associated with visceral fat and inversely associated with IGF‐1 in obese women

MA Bredella, M Torriani, RH Ghomi, BJ Thomas… - …, 2011 - Wiley Online Library
Recent studies have demonstrated an important physiologic link between bone and fat.
Bone and fat cells arise from the same mesenchymal precursor cell within bone marrow …

Fat, adipokines, bone structure and bone regulatory factors associations in obesity

T Vilaca, A Evans, F Gossiel, M Paggiosi… - European Journal of …, 2022 - academic.oup.com
Abstract Context Obese (OB) adults (BMI≥ 30) have a higher bone mineral density (BMD)
and more favourable bone microarchitecture than normal-weight (NW) adults (BMI 18.5 …

Obesity alters cortical and trabecular bone density and geometry in women

D Sukumar, Y Schlussel, CS Riedt, C Gordon… - Osteoporosis …, 2011 - Springer
The goal in this study was to determine the relationship between body mass index and
trabecular and cortical bone using quantitative computed tomography. A higher body mass …

In men with obesity, T2DM is associated with poor trabecular microarchitecture and bone strength and low bone turnover

F Vigevano, G Gregori, G Colleluori… - The Journal of …, 2021 - academic.oup.com
Abstract Introduction Obesity and type 2 Diabetes (T2D) are both associated with greater
bone mineral density (BMD) but increased risk of fractures. The effect of the combination of …

Association between obesity and bone mineral density by gender and menopausal status

MR Salamat, AH Salamat… - Endocrinology and …, 2016 - synapse.koreamed.org
Background We investigated whether there were gender differences in the effect of obesity
on bone mineral density (BMD) based on menopausal status. Methods We assessed 5,892 …

Abdominal fat is associated with lower bone formation and inferior bone quality in healthy premenopausal women: a transiliac bone biopsy study

A Cohen, DW Dempster, RR Recker… - The Journal of …, 2013 - academic.oup.com
Context: The conventional view that obesity is beneficial for bone strength has recently been
challenged by studies that link obesity, particularly visceral obesity, to low bone mass and …

The relationship of fat distribution and insulin resistance with lumbar spine bone mass in women

FJA de Paula, IM de Araujo, AL Carvalho, J Elias Jr… - PloS one, 2015 - journals.plos.org
Bone marrow harbors a significant amount of body adipose tissue (BMAT). While BMAT
might be a source of energy for bone modeling and remodeling, its increment can also …

Difference in the effect of adiposity on bone density between pre-and postmenopausal women

T Douchi, S Yamamoto, T Oki, K Maruta, R Kuwahata… - Maturitas, 2000 - Elsevier
Objectives: Elevated bone mineral density (BMD) in obese women is partially attributable to
the higher circulating estrogen levels derived from extraglandular aromatization in adipose …