Objective: To assess various biochemical markers of myocardial damage. Methods and
Results: Before routinely using any test as a biochemical marker of myocardial damage, the …

Testing for the diagnosis of acute myocardial infarction and other diseases included in the
spectrum of the so-called “acute coronary syndrome” is rapidly changing from the traditional …

Abstract Knowledge of the pathophysiology of ischemic heart disease has advanced in
parallel with awareness of the significant limitations inherent in clinical assessment …

The role of biochemical markers in the diagnosis of acute coronary syndromes has
increased considerably in the past decade. The World Health Organization previously …

M odern medical practice requires rapid decisions. Patients must be triaged faster, treated
more expeditiously, and discharged earlier. Diagnostic tests used to evaluate patients with …

Measurement of cardiac markers in blood has been the mainstay for diagnosis of acute
myocardial infarction for nearly 50 years. The field has evolved from measurement of …

BACKGROUND: The measurement of proteins in blood to reflect damage to the heart is one
of the most successful examples of easily measured biomarkers identifying a serious major …

For many years cardiac markers have been used to classify whether chest pain is
attributable to acute myocardial infarction or not. However massive, myocardial infarction is …

We studied the content and distribution of heart-specific markers troponin I and troponin T in
relation to conventional non–heart specific myoglobin and alpha-hydroxybutyric acid …

Several assumptions about elevations of macromolecular markers of myocardial injury in
blood require critical consideration. The dichotomy of modest, persistent elevations of …