Antimicrobial peptides in the battle against orthopedic implant-related infections: A review
Prevention of orthopedic implant-related infections is a major medical challenge, particularly
due to the involvement of biofilm-encased and multidrug-resistant bacteria. Current …
due to the involvement of biofilm-encased and multidrug-resistant bacteria. Current …
The potential of surface-immobilized antimicrobial peptides for the enhancement of orthopaedic medical devices: a review
B Skerlavaj, G Boix-Lemonche - Antibiotics, 2023 - mdpi.com
Due to the well-known phenomenon of antibiotic resistance, there is a constant need for
antibiotics with novel mechanisms and different targets respect to those currently in use. In …
antibiotics with novel mechanisms and different targets respect to those currently in use. In …
The overview of antimicrobial peptide‐coated implants against oral bacterial infections
Z Sun, L Ma, X Sun, AJ Sloan… - …, 2023 - Wiley Online Library
Dental implants are the most common therapeutic approach for resolving tooth loss and
damage. Despite technical advances in treatment, implant failure rates can be as high as …
damage. Despite technical advances in treatment, implant failure rates can be as high as …
Evaluation of free or anchored antimicrobial peptides as candidates for the prevention of orthopaedic device‐related infections
F D'Este, D Oro, G Boix‐Lemonche… - Journal of Peptide …, 2017 - Wiley Online Library
The prevention of implant‐associated infection, one the most feared complications in
orthopaedic surgery, remains a major clinical challenge and urges development of effective …
orthopaedic surgery, remains a major clinical challenge and urges development of effective …
Shaping the Future of Antimicrobial Therapy: Harnessing the Power of Antimicrobial Peptides in Biomedical Applications
Antimicrobial peptides (AMPs) have emerged as a promising class of bioactive molecules
with the potential to combat infections associated with medical implants and biomaterials …
with the potential to combat infections associated with medical implants and biomaterials …
In vivo antibacterial efficacy of antimicrobial peptides modified metallic Implants─ Systematic review and meta-analysis
AK Sandhu, Y Yang, WW Li - ACS Biomaterials Science & …, 2022 - ACS Publications
Biomaterial-associated infection is difficult to detect and brings consequences that can lead
to morbidity and mortality. Bacteria can adhere to the implant surface, grow, and form …
to morbidity and mortality. Bacteria can adhere to the implant surface, grow, and form …
Application of antimicrobial peptides on biomedical implants: Three ways to pursue peptide coatings
MG Drexelius, I Neundorf - International Journal of Molecular Sciences, 2021 - mdpi.com
Biofilm formation and inflammations are number one reasons of implant failure and cause a
severe number of postoperative complications every year. To functionalize implant surfaces …
severe number of postoperative complications every year. To functionalize implant surfaces …
Strategies for antimicrobial peptide coatings on medical devices: A review and regulatory science perspective
M Kazemzadeh-Narbat, H Cheng… - Critical reviews in …, 2021 - Taylor & Francis
Indwelling and implanted medical devices are subject to contamination by microbial
pathogens during surgery, insertion or injection, and ongoing use, often resulting in severe …
pathogens during surgery, insertion or injection, and ongoing use, often resulting in severe …
Antimicrobial peptides for topical treatment of osteomyelitis and implant-related infections: study in the spongy bone
P Melicherčík, O Nešuta, V Čeřovský - Pharmaceuticals, 2018 - mdpi.com
We examined the benefits of short linear α-helical antimicrobial peptides (AMPs) invented in
our laboratory for treating bone infection and preventing microbial biofilm formation on …
our laboratory for treating bone infection and preventing microbial biofilm formation on …
Chimeric peptides as implant functionalization agents for titanium alloy implants with antimicrobial properties
Implant-associated infections can have severe effects on the longevity of implant devices
and they also represent a major cause of implant failures. Treating these infections …
and they also represent a major cause of implant failures. Treating these infections …
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