Prevention of orthopedic implant-related infections is a major medical challenge, particularly
due to the involvement of biofilm-encased and multidrug-resistant bacteria. Current …

Due to the well-known phenomenon of antibiotic resistance, there is a constant need for
antibiotics with novel mechanisms and different targets respect to those currently in use. In …

Dental implants are the most common therapeutic approach for resolving tooth loss and
damage. Despite technical advances in treatment, implant failure rates can be as high as …

The prevention of implant‐associated infection, one the most feared complications in
orthopaedic surgery, remains a major clinical challenge and urges development of effective …

Antimicrobial peptides (AMPs) have emerged as a promising class of bioactive molecules
with the potential to combat infections associated with medical implants and biomaterials …

Biomaterial-associated infection is difficult to detect and brings consequences that can lead
to morbidity and mortality. Bacteria can adhere to the implant surface, grow, and form …

Biofilm formation and inflammations are number one reasons of implant failure and cause a
severe number of postoperative complications every year. To functionalize implant surfaces …

Indwelling and implanted medical devices are subject to contamination by microbial
pathogens during surgery, insertion or injection, and ongoing use, often resulting in severe …

We examined the benefits of short linear α-helical antimicrobial peptides (AMPs) invented in
our laboratory for treating bone infection and preventing microbial biofilm formation on …

Implant-associated infections can have severe effects on the longevity of implant devices
and they also represent a major cause of implant failures. Treating these infections …