Ovarian cancer (OC) is one of the leading causes of female cancer death. Recent studies
have documented its extensive variations as a disease entity, in terms of cell or tissue of …

Ovarian cancer (OC) is a heterogeneous malignancy with various etiology, histopathology,
and biological feature. Despite accumulating understanding of OC in the post-genomic era …

Despite decades of research, ovarian cancer is still associated with unacceptably high
mortality rates, which must be addressed by novel therapeutic approaches. One avenue …

Despite advances in understanding of ovarian cancer biology, the progress in translation of
research findings into new therapies is still slow. It is associated in part with limitations of …

Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy and the fifth most
common cause of female cancer death in the United States. Although important advances in …

The complexity and heterogeneity of ovarian cancer cases are difficult to reproduce in in
vitro studies, which cannot adequately elucidate the molecular events involved in tumor …

The use of primary patient-derived organoids for drug sensitivity and resistance testing could
play an important role in precision cancer medicine. We developed expandable ovarian …

Despite many improvements in ovarian cancer diagnosis and treatment, until now,
conventional chemotherapy and new biological drugs have not been shown to cure the …

Ovarian cancer has the highest mortality of all of the gynecological malignancies. There are
several distinct histotypes of this malignancy characterized by specific molecular events and …

Ovarian cancer (OC) represents the most dismal gynecological cancer. Pathobiology is
poorly understood, mainly due to lack of appropriate study models. Organoids, defined as …