[HTML][HTML] Inflammation in human heart failure: major mediators and therapeutic targets

M Reina-Couto, P Pereira-Terra… - Frontiers in …, 2021 - frontiersin.org
Inflammation has been recognized as a major pathophysiological contributor to the entire
spectrum of human heart failure (HF), including HF with reduced ejection fraction, HF with …

Inflammation in Heart Failure: JACC State-of-the-Art Review

SP Murphy, R Kakkar, CP McCarthy… - Journal of the American …, 2020 - jacc.org
It has long been observed that heart failure (HF) is associated with measures of systemic
inflammation. In recent years, there have been significant advancements in our …

[HTML][HTML] Inflammatory cytokines, immune cells, and organ interactions in heart failure

H Li, C Chen, DW Wang - Frontiers in physiology, 2021 - frontiersin.org
Despite mounting evidence demonstrating the significance of inflammation in the
pathophysiological mechanisms of heart failure (HF), most large clinical trials that target the …

Inflammation as a therapeutic target in heart failure? A scientific statement from the Translational Research Committee of the Heart Failure Association of the …

S Heymans, E Hirsch, SD Anker… - European journal of …, 2009 - Wiley Online Library
The increasing prevalence of heart failure poses enormous challenges for health care
systems worldwide. Despite effective medical interventions that target neurohumoral …

Key inflammatory mechanisms underlying heart failure

C Riehle, J Bauersachs - Herz, 2019 - Springer
Inflammation plays a central role in the development of heart failure, especially in heart
failure with preserved ejection fraction (HFpEF). Furthermore, the inflammatory response …

Inflammatory mediators in chronic heart failure: an overview

SD Anker, S von Haehling - Heart, 2004 - heart.bmj.com
Chronic heart failure (CHF) represents a major public health burden, and its prognosis is
comparable to that of different malignant diseases. Our understanding of CHF has …

The role of inflammation and cell death in the pathogenesis, progression and treatment of heart failure

A Briasoulis, E Androulakis, T Christophides… - Heart failure …, 2016 - Springer
Chronic inflammation underlies a variety of seemingly unrelated conditions including
coronary artery disease. The interest in exploring the role of inflammation in heart failure …

Chronic heart failure and inflammation: what do we really know?

SA Dick, S Epelman - Circulation research, 2016 - Am Heart Assoc
As a greater proportion of patients survive their initial cardiac insult, medical systems
worldwide are being faced with an ever-growing need to understand the mechanisms …

Various aspects of inflammation in heart failure

M Dutka, R Bobiński, I Ulman-Włodarz, M Hajduga… - Heart failure …, 2020 - Springer
Despite significant advances in the prevention and treatment of heart failure (HF), the
prognosis in patients who have been hospitalised on at least one occasion due to …

Systemic inflammation in heart failure–the whys and wherefores

A Yndestad, J Kristian Damås, E Øie, T Ueland… - Heart failure …, 2006 - Springer
Patients with chronic heart failure (HF) are characterized by systemic inflammation, as
evident by raised circulating levels of several inflammatory cytokines with increasing levels …