[HTML][HTML] Systems medicine for precise targeting of glioblastoma

J Zeng, XX Zeng - Molecular Biotechnology, 2023 - Springer
Glioblastoma (GBM) is a malignant cancer that is fatal even after standard therapy and the
effects of current available therapeutics are not promising due its complex and evolving …

[HTML][HTML] The advances in glioblastoma on-a-chip for therapy approaches

AH Alves, MP Nucci, JB Mamani, NME Valle… - Cancers, 2022 - mdpi.com
Simple Summary This systematic review showed different therapeutic approaches to
glioblastoma on-a-chip with varying levels of complexity, answering, from the simplest …

Role of nanobiotechnology in the personalized management of glioblastoma multiforme

KK Jain - Nanomedicine, 2011 - Taylor & Francis
Along with the introduction of innovative methods, there is a need to choose the best treat
ment suitable for an individual (ie, personalized medicine)[2]. Personalized treatment is …

[HTML][HTML] Artificial intelligence and precision medicine: a new frontier for the treatment of brain tumors

AK Philip, BA Samuel, S Bhatia, SAM Khalifa… - Life, 2022 - mdpi.com
Brain tumors are a widespread and serious neurological phenomenon that can be life-
threatening. The computing field has allowed for the development of artificial intelligence …

Could Be Systems-Directed Therapy Approaches Promising in Glioblastoma Patients?

O Grauer, P Hau - From Molecular to Modular Tumor Therapy: Tumors are …, 2010 - Springer
Glioblastoma bears one of the most severe prognoses of human cancers. At this time, the
available therapy is directed against specific pathological mechanisms of these tumors, as …

[HTML][HTML] Current understanding of gliomagenesis: from model to mechanism

J Luo, M Junaid, N Hamid, JJ Duan… - International Journal of …, 2022 - ncbi.nlm.nih.gov
Glioma, a kind of central nervous system (CNS) tumor, is hard to cure and accounts for 32%
of all CNS tumors. Establishing a stable glioma model is critically important to investigate the …

[HTML][HTML] Personalized regulation of glioblastoma cancer stem cells based on biomedical technologies: From theory to experiment

I Bryukhovetskiy, A Ponomarenko… - International …, 2018 - spandidos-publications.com
Glioblastoma multiforme (GBM) is one of the most aggressive brain tumors. GBM
represents> 50% of primary tumors of the nervous system and~ 20% of intracranial …

A computational approach for designing combination therapy in combating glioblastoma

T Truong, P Moscato, N Noman - 2019 IEEE congress on …, 2019 - ieeexplore.ieee.org
The signalling pathways of the glioblastoma (GBM) microenvironment play critical roles in
the origin and progress of the disease. Recently, it has been shown in in silico experiments …

Designing optimal combination therapy for personalised glioma treatment

N Noman, P Moscato - Memetic Computing, 2020 - Springer
Background Like it happens in other tumours, glioma cells co-evolve in a microenvironment
consisting of bona fide tumour cells as well as a range of parenchymal cells, which produces …

[HTML][HTML] A Preclinical Pipeline for Translational Precision Medicine—Experiences from a Transdisciplinary Brain Tumor Stem Cell Project

A Vargas-Toscano, C Janiak, M Sabel… - Journal of Personalized …, 2021 - mdpi.com
Efficient transdisciplinary cooperation promotes the rapid discovery and clinical application
of new technologies, especially in the competitive sector of oncology. In this review, written …