Exploring the synthetic biology potential of bacteriophages for engineering non-model bacteria
Non-model bacteria like Pseudomonas putida, Lactococcus lactis and other species have
unique and versatile metabolisms, offering unique opportunities for Synthetic Biology …
unique and versatile metabolisms, offering unique opportunities for Synthetic Biology …
[HTML][HTML] Bacteriophage-based synthetic biology for the study of infectious diseases
Highlights•Multidrug-resistant infections have sparked a renewed interest in
bacteriophages.•Synthetic biology has enabled technologies for next-generation phage …
bacteriophages.•Synthetic biology has enabled technologies for next-generation phage …
Phage therapy in the era of synthetic biology
EM Barbu, KC Cady, B Hubby - Cold Spring Harbor …, 2016 - cshperspectives.cshlp.org
For more than a century, bacteriophage (or phage) research has enabled some of the most
important discoveries in biological sciences and has equipped scientists with many of the …
important discoveries in biological sciences and has equipped scientists with many of the …
Harnessing stepping-stone hosts to engineer, select, and reboot synthetic bacteriophages in one pot
Advances in synthetic genomics have led to a great demand for genetic manipulation.
Trimming any process to simplify and accelerate streamlining of genetic code into life holds …
Trimming any process to simplify and accelerate streamlining of genetic code into life holds …
Cross-genus rebooting of custom-made, synthetic bacteriophage genomes in L-form bacteria
S Kilcher, P Studer, C Muessner… - Proceedings of the …, 2018 - National Acad Sciences
Engineered bacteriophages provide powerful tools for biotechnology, diagnostics, pathogen
control, and therapy. However, current techniques for phage editing are experimentally …
control, and therapy. However, current techniques for phage editing are experimentally …
Phage-based applications in synthetic biology
Bacteriophage research has been instrumental to advancing many fields of biology, such as
genetics, molecular biology, and synthetic biology. Many phage-derived technologies have …
genetics, molecular biology, and synthetic biology. Many phage-derived technologies have …
Escherichia coli as a host for metabolic engineering
Over the past century, Escherichia coli has become one of the best studied organisms on
earth. Features such as genetic tractability, favorable growth conditions, well characterized …
earth. Features such as genetic tractability, favorable growth conditions, well characterized …
The next generation of synthetic biology chassis: moving synthetic biology from the laboratory to the field
BL Adams - ACS Synthetic Biology, 2016 - ACS Publications
Escherichia coli (E. coli) has played a pivotal role in the development of genetics and
molecular biology as scientific fields. It is therefore not surprising that synthetic biology (SB) …
molecular biology as scientific fields. It is therefore not surprising that synthetic biology (SB) …
Chasing bacterial chassis for metabolic engineering: a perspective review from classical to non‐traditional microorganisms
The last few years have witnessed an unprecedented increase in the number of novel
bacterial species that hold potential to be used for metabolic engineering. Historically …
bacterial species that hold potential to be used for metabolic engineering. Historically …
Enhancing phage therapy through synthetic biology and genome engineering
BR Lenneman, J Fernbach, MJ Loessner, TK Lu… - Current Opinion in …, 2021 - Elsevier
Highlights•Synthetic biology enables efficient phage genome engineering.•Phages with
tunable host range and antimicrobial payload delivery enhance efficacy.•Phage design …
tunable host range and antimicrobial payload delivery enhance efficacy.•Phage design …