Stroke is a heterogeneous syndrome, and determining risk factors and treatment depends
on the specific pathogenesis of stroke. Risk factors for stroke can be categorized as …

Risk factor modification remains as the principal aspect of care for stroke prevention.
Understanding of risk factors has advanced and several options are now available to treat …

In the present historical review, we highlight several papers outlining contributions of the
Framingham Heart Study (FHS) over the span of nearly 7 decades to our understanding of …

Understanding the genetic risk factors for stroke is an essential step to decipher the
underlying mechanisms, facilitate the identification of novel therapeutic targets, and optimize …

Interrelationships between genetic and biochemical factors underlying ischemic stroke and
ischemic heart disease are poorly understood. We: 1) undertook the most comprehensive …

Stroke represents an enormous health problem worldwide. It describes a clinical syndrome
which can be caused by a number of different pathologies, rather than a single disease …

Stroke is the third leading cause of death and the leading cause of chronic disability in the
United States. In the past several decades, case series, case-control studies, and …

Stroke genetics includes several topics of clinical interest, including (1) molecular genetic
variations affecting risk of monogenic stroke syndromes;(2) molecular genetic variations …

Background and Purpose Although familial history of stroke is generally perceived to be an
important marker of stroke risk, very few epidemiological studies have been published to …

Background and Purpose: Assessing whether modifiable risk factors are causally associated
with stroke risk is important in planning public health measures, but determining causality …