This thoroughly revised and updated reference addresses the drugs and chemicals causing
malformations and congenital anomalies in the human fetus-comprehensively reviewing …

There have been amazing advances in embryology, teratology, reproductive biology,
genetics, and epidemiology in the past 50 years that have provided scientists and clinicians …

Exposure of the developing conceptus to selected environmental agents can lead to
deleterious and often times lethal birth defects. These malformations result in serious …

Having received the invitation from Springer-Verlag to produce a volume on drug-induced
birth defects for the Handbook of Experimental Pharmacology, we asked ourselves what …

Crucial morphogenetic processes during the blastogenesis period, which extends
throughout the first 4 wk of development, from fertilization until the end of the gastrulation …

Discusses the teratology of congenital malformations in humans and the establishment of
their environmental causes. The article first explores various aspects of congenital …

Within the past decade, interest has increased markedly in the elucidation of mechanisms
whereby drugs and other chemicals can alter the normal developmental pattern of the …

The assumption that major fetal malformations are indicative of a chemical's teratogenic
potential was not supported by a literature review of teratology studies conducted in mice. In …

Prerequisite to understanding abnormal development is a firm grasp of normal development.
An overview of normal mammalian development is provided in this volume by Donahoe and …

Congenital anomalies are an important cause of infant mortality and disability.
Developmental exposure to environmental contaminants is thought to increase the risk for …