Lung function estimates in idiopathic pulmonary fibrosis: the potential for a simple classification
JJ Egan, FJ Martinez, AU Wells, T Williams - Thorax, 2005 - thorax.bmj.com
The gene encoding A Disintegrin And Metalloprotease (ADAM) 33 was the first asthma
susceptibility gene to be discovered by positional cloning. 1 In 460 families enriched with …
susceptibility gene to be discovered by positional cloning. 1 In 460 families enriched with …
Pulmonary fibrosis in the era of stratified medicine
SK Mathai, CA Newton, DA Schwartz, CK Garcia - Thorax, 2016 - thorax.bmj.com
Both common and rare variants contribute to the genetic architecture of pulmonary fibrosis.
Genome-wide association studies have identified common variants, or those with a minor …
Genome-wide association studies have identified common variants, or those with a minor …
Symptoms and the early diagnosis of lung cancer
SS Birring, MD Peake - Thorax, 2005 - thorax.bmj.com
The gene encoding A Disintegrin And Metalloprotease (ADAM) 33 was the first asthma
susceptibility gene to be discovered by positional cloning. 1 In 460 families enriched with …
susceptibility gene to be discovered by positional cloning. 1 In 460 families enriched with …
Longitudinal lung function and gas transfer in individuals with idiopathic pulmonary fibrosis: a genome-wide association study
Background Idiopathic pulmonary fibrosis (IPF) is an incurable lung disease characterised
by progressive scarring leading to alveolar stiffness, reduced lung capacity, and impeded …
by progressive scarring leading to alveolar stiffness, reduced lung capacity, and impeded …
Nitric oxide, hypoxia, and superoxide: the good, the bad, and the ugly!
RA Dweik - Thorax, 2005 - thorax.bmj.com
The gene encoding A Disintegrin And Metalloprotease (ADAM) 33 was the first asthma
susceptibility gene to be discovered by positional cloning. 1 In 460 families enriched with …
susceptibility gene to be discovered by positional cloning. 1 In 460 families enriched with …
Molecular classification of idiopathic pulmonary fibrosis: personalized medicine, genetics and biomarkers
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive fibrotic lung disease
associated with high morbidity and poor survival. Characterized by substantial disease …
associated with high morbidity and poor survival. Characterized by substantial disease …
Genetics of fibrosing lung diseases
JC Grutters, RM Du Bois - European Respiratory Journal, 2005 - Eur Respiratory Soc
Genetic studies in familial lung fibrosis have demonstrated an association with surfactant
protein C genes: two mutations have been found resulting in protein misfolding and causing …
protein C genes: two mutations have been found resulting in protein misfolding and causing …
Genetic determinants of pulmonary fibrosis: evolving concepts
P Spagnolo, J Grunewald, RM Du Bois - The Lancet Respiratory …, 2014 - thelancet.com
Interstitial lung diseases encompass a wide range of diffuse lung disorders that are often
complicated by the development of pulmonary fibrosis and that can occur in isolation or in …
complicated by the development of pulmonary fibrosis and that can occur in isolation or in …
Genetics of idiopathic pulmonary fibrosis: from mechanistic pathways to personalised medicine
P Spagnolo, V Cottin - Journal of medical genetics, 2017 - jmg.bmj.com
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and ultimately fatal disorder for
which there is no cure. While the disease is by definition idiopathic, accumulating evidence …
which there is no cure. While the disease is by definition idiopathic, accumulating evidence …
Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study
Background Idiopathic pulmonary fibrosis (IPF) is a devastating disease that probably
involves several genetic loci. Several rare genetic variants and one common single …
involves several genetic loci. Several rare genetic variants and one common single …