Introduction: Malaria in pregnancy and postpartum cause maternal mortality and adverse
fetal outcomes. Efficacious and safe antimalarials are needed to treat and prevent such …

Importance of the field: Malaria infection during pregnancy is a major public health problem
worldwide, with 50 million pregnancies exposed to the infection every year. Approximately …

All malaria infections are harmful to both the pregnant mother and the developing fetus. One
in ten maternal deaths in malaria endemic countries are estimated to result from …

In this review we examine the available information on the safety of antimalarials in
pregnancy, from both animal and human studies. The antimalarials that can be used in …

Pregnant women are especially susceptible to malaria infection. Without existing immunity,
severe malaria can develop requiring emergency treatment, and pregnancy loss is common …

Alternative drugs to chloroquine are required to prevent the deleterious effects of malaria in
pregnancy. Fear of potential toxicity has limited antimalarial drug use in pregnancy. Animal …

Few antimalarial drugs have been evaluated extensively in pregnancy because of fears over
toxicity. However, increasing Plasmodium falciparum resistance to chloroquine and …

Please cite this paper as: McGready R, White N, Nosten F. Parasitological efficacy of
antimalarials in the treatment and prevention of falciparum malaria in pregnancy 1998 to …

Abstract Background Malaria caused by Plasmodium falciparum in pregnancy can result in
adverse maternal and fetal sequelae. This review evaluated the adherence of the national …

One hundred and twenty-five million women in malaria-endemic areas become pregnant
each year (see Dellicour et al. PLoS Med 7: e1000221 [2010]) and require protection from …