Elucidation of the Genomic‐Epigenomic Interaction Landscape of Aggressive Prostate Cancer
TK Kumar Mamidi, J Wu, C Hicks - BioMed research …, 2021 - Wiley Online Library
Background. Majority of prostate cancer (PCa) deaths are attributed to localized high‐grade
aggressive tumours which progress rapidly to metastatic disease. A critical unmet need in …
aggressive tumours which progress rapidly to metastatic disease. A critical unmet need in …
Interactions between germline and somatic mutated genes in aggressive prostate cancer
TKK Mamidi, J Wu, C Hicks - Prostate Cancer, 2019 - Wiley Online Library
Prostate cancer (PCa) is the most common diagnosed malignancy and the second leading
cause of cancer‐related deaths among men in the USA. Advances in high‐throughput …
cause of cancer‐related deaths among men in the USA. Advances in high‐throughput …
Mapping the germline and somatic mutation interaction landscape in indolent and aggressive prostate cancers
TKK Mamidi, J Wu, C Hicks - Journal of Oncology, 2019 - Wiley Online Library
Background. A majority of prostate cancers (PCas) are indolent and cause no harm even
without treatment. However, a significant proportion of patients with PCa have aggressive …
without treatment. However, a significant proportion of patients with PCa have aggressive …
An Integrative analysis of chromatin interactions, gene expression and genomic variants identifies 30 likely regulatory variants in Prostate Cancer
Prostate cancer (PC) is the most frequently diagnosed non-skin cancer in the world.
Previous studies showed that genomic alterations represent the most common mechanism …
Previous studies showed that genomic alterations represent the most common mechanism …
Multi-omic profiling of prostate cancer evolution in 39 patients
Q Zhong, T Guo, N Toussaint, U Wagner, K Charmpi… - Cancer Research, 2017 - AACR
The pathological molecular events occurring during prostate cancer (PCa) progression have
not been comprehensively investigated. It remains elusive how genomic aberration is …
not been comprehensively investigated. It remains elusive how genomic aberration is …
Integrating germline and somatic variation information using genomic data for the discovery of biomarkers in prostate cancer
TKK Mamidi, J Wu, C Hicks - BMC cancer, 2019 - Springer
Abstract Background Prostate cancer (PCa) is the most common diagnosed malignancy and
the second leading cause of cancer-related deaths among men in the United States. High …
the second leading cause of cancer-related deaths among men in the United States. High …
Whole-genome and transcriptome sequencing of prostate cancer identify new genetic alterations driving disease progression
Background Global disparities in prostate cancer (PCa) incidence highlight the urgent need
to identify genomic abnormalities in prostate tumors in different ethnic populations including …
to identify genomic abnormalities in prostate tumors in different ethnic populations including …
Integrative multi-omics analysis enables a comprehensive characterization of prostate cancer and unveils metastasis-associated candidate biomarkers
Prostate cancer (PCa), a common malignancy in men, presents a complex and variable
disease landscape, requiring precise evaluation for personalized treatment decisions …
disease landscape, requiring precise evaluation for personalized treatment decisions …
Genomic, epigenomic, and transcriptomic signatures of prostate cancer between African American and European American patients
C Stevens, A Hightower, SG Buxbaum… - Frontiers in …, 2023 - frontiersin.org
Prostate cancer is the second most common cancer in men in the United States, and racial
disparities are greatly observed in the disease. Specifically, African American (AA) patients …
disparities are greatly observed in the disease. Specifically, African American (AA) patients …
From omics to multi-omics approaches for in-depth analysis of the molecular mechanisms of prostate cancer
E Nevedomskaya, B Haendler - International Journal of Molecular …, 2022 - mdpi.com
Cancer arises following alterations at different cellular levels, including genetic and
epigenetic modifications, transcription and translation dysregulation, as well as metabolic …
epigenetic modifications, transcription and translation dysregulation, as well as metabolic …
相关搜索
- interaction landscape prostate cancer
- genomic variants prostate cancer
- discovery of biomarkers prostate cancer
- integrative analysis prostate cancer
- disease progression prostate cancer
- gene expression prostate cancer
- genomic variants chromatin interactions
- american patients prostate cancer
- molecular basis prostate cancer
- transcriptome sequencing prostate cancer
- chromatin interactions prostate cancer
- genomic analyses prostate cancer
- variation information prostate cancer
- disease heterogeneity prostate cancer
- candidate biomarkers prostate cancer
- whole genome prostate cancer