Exploring the Therapeutic Potential of Bromelain: Applications, Benefits, and Mechanisms

U Kansakar, V Trimarco, MV Manzi, E Cervi, P Mone… - Nutrients, 2024 - mdpi.com
Bromelain is a mixture of proteolytic enzymes primarily extracted from the fruit and stem of
the pineapple plant (Ananas comosus). It has a long history of traditional medicinal use in …

Recent advances and insights into bromelain processing, pharmacokinetics and therapeutic uses

A Colletti, S Li, M Marengo, S Adinolfi, G Cravotto - Applied Sciences, 2021 - mdpi.com
Bromelain is a mixture of proteolytic enzymes that is extracted primarily from pineapples. It is
present in almost all the aerial parts of the plant—the peels, leaves, stems and fruit …

Bromelain: an overview

BK Bhattacharyya - 2008 - nopr.niscpr.res.in
Bromelain is a crude extract from the fruit or stem of pineapple [Ananas comosus (Linn.)
Merr] plant. It consists of different closely related proteinases which are good anti …

A review on chemistry, therapeutic applications, extraction & purification of bromelain

A Nelson, A Peter, F Saju - International Journal of …, 2022 - saapjournals.org
This review focused on the usage of bromelain in numerous applications, as well as the
most recent literature on the chemistry, extraction, and purification of bromelain from …

Bromelain a potential bioactive compound: a comprehensive overview from a pharmacological perspective

AJ Chakraborty, S Mitra, TE Tallei, AM Tareq, F Nainu… - Life, 2021 - mdpi.com
Bromelain is an effective chemoresponsive proteolytic enzyme derived from pineapple
stems. It contains several thiol endopeptidases and is extracted and purified via several …

Bromelain: biochemistry, pharmacology and medical use

HR Maurer - Cellular and Molecular Life Sciences CMLS, 2001 - Springer
Bromelain is a crude extract from the pineapple that contains, among other components,
various closely related proteinases, demonstrating, in vitro and in vivo, antiedematous …

Systemic enzyme therapy: fact or fiction? A review with focus on bromelains, proteolytic enzymes from the pineapple plant

P Meiser, Z Xu, G Kirsch, C Jacob - … Advances in Redox Active Plant and …, 2014 - Springer
In this chapter, bromelain, a crude multi-component extract isolated from the stems of the
pineapple plant, takes us on a tour through rather unusual therapeutic approaches and …

Current Uses of Bromelain in Children: A Narrative Review

C Locci, E Chicconi, R Antonucci - Children, 2024 - mdpi.com
Bromelain is a complex natural mixture of sulfhydryl-containing proteolytic enzymes that can
be extracted from the stem or fruit of the pineapple. This compound is considered a safe …

Stability, purification, and applications of bromelain: A review

LC de Lencastre Novaes, AF Jozala… - Biotechnology …, 2016 - Wiley Online Library
Bromelain is a cysteine protease found in pineapple tissue. Because of its anti‐inflammatory
and anti‐cancer activities, as well as its ability to induce apoptotic cell death, bromelain has …

Bromelain: A review of its mechanisms, pharmacological effects and potential applications

V Kumar, B Mangla, S Javed, W Ahsan, P Kumar… - Food & function, 2023 - pubs.rsc.org
The utilization of plant-derived supplements for disease prevention and treatment has long
been recognized because of their remarkable potential. Ananas comosus, commonly known …